AB5421II100

Vesicular Glutamate Transporter 3 (VGLUT3), Rabbit anti-Mouse, Human, Rat, Polyclonal, Millipore Sigma™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 AB5421II100-Each-of-1 In Stock ₹ 42,676.47

AB5421II100 - Each of 1

₹ 42,676.47

In Stock

Quantity

1

Base Price: ₹ 42,676.47

GST (18%): ₹ 7,681.765

Total Price: ₹ 50,358.235

Antigen

Vesicular Glutamate Transporter 3 (VGLUT3)

Classification

Polyclonal

Dilution

Western Blotting Analysis: A 1:500 dilution from a representative lot detected Vesicular Glutamate Transporter 3 (VGLUT3) in PC12 cell lysate.Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution from a representative lot detected Vesicular Glutamate Transporter 3 (VGLUT3) in rat brain and human brain tissue sections.Immunocytochemistry Analysis: A 1:1,000 dilution from a representative lot detected Vesicular Glutamate Transporter 3 (VGLUT3) in PC12 cells.

Gene Alias

Solute carrier family 17 member 8;VGluT3

Host Species

Rabbit

Molecular Weight of Antigen

∽ 60 kDa observed; 64.76 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Quantity

100 μg

Research Discipline

Neuroscience

Test Specificity

This rabbit polyclonal antibody specifically detects Vesicular glutamate transporter 3(VGluT3). It targets an epitope with in 13 amino acids from the C-terminal region.

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols

Slc17a8;Vglut3

Immunogen

KLH-conjugated linear peptide corresponding to 13 amino acids from the C-terminal region of rat Vesicular glutamate transporter 3 (VGluT3).

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Mouse, Human, Rat

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Description

  • Anti-Vesicular Glutamate Transporter 3 (VGLUT3), Cat
  • No
  • AB5421-II, is a highly specific rabbit polyclonal antibody that targets Vesicular glutamate transporter 3 and has been tested foe use in Immunocytochemistry, Immunohistochemistry (Paraffin), and Western Blotting
  • Vesicular glutamate transporter 3 (UniProt Q7TSF2; also known as Solute carrier family 17 member 8, VGluT3) is encoded by the Slc17a8 (also known as Vglut3) gene (Gene ID 266767) in rat species
  • VGluTs are proton-dependent carriers that are responsible for the upload of the major excitatory neurotransmitter glutamate into synaptic vesicles within presynaptic terminals to allow later regulated release at the synaptic cleft
  • VGluT3 is a multi-pass synaptic vesicle membrane protein that mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neurons
  • Rat VGluT3 has 12 helical, 7 cytoplasmic, and 6 vesicular domains
  • It is structurally similar to VGluT1 and -2, but differs in its distribution pattern
  • Unlike VGluT1 and 2 that rely on interactions with the endocytic machinery for recycling, but remain almost exclusively axonal, VGluT3 can target to the cell body and dendrites, as well as the axon of certain neurons and is implicated in the retrograde synaptic release of glutamate
  • VGluT3 displays a very restricted localization and is not present in known glutamatergic neurons, but is found in cholinergic neurons in the caudate-putamen and in serotonergic neurons in the raphe nucleus
  • VGluT3 is localized over vesicle clusters in both symmetric (inhibitory or modulatory) and asymmetric (excitatory) synapses
  • (Ref.: Herzog, E et al
  • (2004)
  • Neuroscience
  • 123(4):983-1002; Seal, RP et al
  • (2008)
  • Neuron 57(2); 263-275).

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AB5421II100

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Antigen:
Vesicular Glutamate Transporter 3 (VGLUT3)

Classification:
Polyclonal

Dilution:
Western Blotting Analysis: A 1:500 dilution from a representative lot detected Vesicular Glutamate Transporter 3 (VGLUT3) in PC12 cell lysate.Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution from a representative lot detected Vesicular Glutamate Transporter 3 (VGLUT3) in rat brain and human brain tissue sections.Immunocytochemistry Analysis: A 1:1,000 dilution from a representative lot detected Vesicular Glutamate Transporter 3 (VGLUT3) in PC12 cells.

Gene Alias:
Solute carrier family 17 member 8;VGluT3

Host Species:
Rabbit

Molecular Weight of Antigen:
∽ 60 kDa observed; 64.76 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Quantity:
100 μg

Research Discipline:
Neuroscience

Test Specificity:
This rabbit polyclonal antibody specifically detects Vesicular glutamate transporter 3(VGluT3). It targets an epitope with in 13 amino acids from the C-terminal region.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
Slc17a8;Vglut3

Immunogen:
KLH-conjugated linear peptide corresponding to 13 amino acids from the C-terminal region of rat Vesicular glutamate transporter 3 (VGluT3).

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse, Human, Rat

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Antigen:
Vesicular Glutamate Transporter 3 (VGLUT3)

Classification:
Polyclonal

Dilution:
Western Blotting Analysis: A 1:500 dilution from a representative lot detected Vesicular Glutamate Transporter 3 (VGLUT3) in PC12 cell lysate.Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution from a representative lot detected Vesicular Glutamate Transporter 3 (VGLUT3) in rat brain and human brain tissue sections.Immunocytochemistry Analysis: A 1:1,000 dilution from a representative lot detected Vesicular Glutamate Transporter 3 (VGLUT3) in PC12 cells.

Gene Alias:
Solute carrier family 17 member 8;VGluT3

Host Species:
Rabbit

Molecular Weight of Antigen:
∽ 60 kDa observed; 64.76 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Quantity:
25 μg

Research Discipline:
Neuroscience

Test Specificity:
This rabbit polyclonal antibody specifically detects Vesicular glutamate transporter 3(VGluT3). It targets an epitope with in 13 amino acids from the C-terminal region.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
Slc17a8;Vglut3

Immunogen:
KLH-conjugated linear peptide corresponding to 13 amino acids from the C-terminal region of rat Vesicular glutamate transporter 3 (VGluT3).

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse, Human, Rat

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Dilution:
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Molecular Weight of Antigen:
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Conjugate:
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Immunogen:
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Purification Method:
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Regulatory Status:
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Primary or Secondary:
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Target Species:
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