ABN91025UG
Aquaporin 4, Rabbit anti-Rat, Mouse, Human, Polyclonal, Millipore Sigma™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABN91025UG-Each-of-1 | In Stock | ₹ 16,456.61 |
ABN91025UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,456.61
GST (18%): ₹ 2,962.19
Total Price: ₹ 19,418.80
Antigen
Aquaporin 4
Classification
Polyclonal
Dilution
Immunohistochemistry (Paraffin) Analysis : A 1:1,000 dilution from a representative lot detected Aquaporin 4 in rat cerebral cortex tissue.Western Blotting Analysis: A 1:500 dilution from a representative lot detected Aquaporin 4 in human brain tissue lysate.
Gene Alias
AQP-4;Mercurial-insensitive water channel;MIWC
Host Species
Rabbit
Molecular Weight of Antigen
∽34.0 kDa observed; 34.48 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity
25 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_001257487.1
Target Species
Rat, Mouse, Human
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine, 150 mM NaCl (pH 7.4) with 0.05% sodium azide.
Gene Symbols
Aqp4
Immunogen
GST/HIs-taged recombinant fragment corresponding to 75 amino acids from the C-terminal region of rat Aquaporin-4.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This rabbit polyclonal antiody detects Aquaporin-4. It targets an epitope with in 75 amino acids from the C-terminal.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Related Products
Description
- Anti-Aquaporin 4, Cat
- No
- ABN910, is a highly specific rabbit polyclonal antibody that targets Aquaporin 4 and has been tested for use in Immunohistochemistry (Paraffin) and Western Blotting
- Aquaporin-4 (UniProt: P47863; also known as AQP-4, Mercurial-insensitive water channel, MIWC) is encoded by the Aqp4 gene (Gene ID: 25293) in rat
- Aquaporin-4 is a multi-pass membrane homotetrameric protein that forms a water-specific channel and serves as an osmoreceptor that regulates body water balance and mediates water flow within the central nervous system
- Its extracellular domains are localized to amino acids 58-64, 137-155, and 206-231); its transmembrane domains are in amino acids 37-57, 65-85, 116-136, 156-176, 185-205, and 232-252); and the cytoplasmic domain is in amino acids 1-36, 86-115, 177-184, and 253-323)
- Aquaporin-4 is largely expressed in the brain and the skeletal muscle and at lower levels in heart, kidney, and lung tissue
- Phosphorylation of Aquaporin-4 at Serine 180 by protein kinase C is shown to reduce conductance by about 50%, whereas phosphorylation at Serine 111 by protein kinase G in response to glutamate can increase conductance by about 40%
- Two isoforms of Aquaporin-4 have been described that are produced by alternative splicing
- Antibodies to Aquaporin-4 can serve as useful serum markers to distinguishing neuromyelitis optica (NM) from multiple sclerosis
- Clone mCCD does not cause redistribution of Aquaporin-4 and also it does not affect coaggregation astrocytic CD32-B and Aquaporin-4
- (Ref.: Hinson, SR et al
- (2017)
- Proc
- Natl
- Acad
- Sci
- USA 114(21); 5491-5496).
Compare Similar Items
Show Difference
Antigen: Aquaporin 4
Classification: Polyclonal
Dilution: Immunohistochemistry (Paraffin) Analysis : A 1:1,000 dilution from a representative lot detected Aquaporin 4 in rat cerebral cortex tissue.Western Blotting Analysis: A 1:500 dilution from a representative lot detected Aquaporin 4 in human brain tissue lysate.
Gene Alias: AQP-4;Mercurial-insensitive water channel;MIWC
Host Species: Rabbit
Molecular Weight of Antigen: ∽34.0 kDa observed; 34.48 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 25 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_001257487.1
Target Species: Rat, Mouse, Human
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine, 150 mM NaCl (pH 7.4) with 0.05% sodium azide.
Gene Symbols: Aqp4
Immunogen: GST/HIs-taged recombinant fragment corresponding to 75 amino acids from the C-terminal region of rat Aquaporin-4.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antiody detects Aquaporin-4. It targets an epitope with in 75 amino acids from the C-terminal.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Antigen:
Aquaporin 4
Classification:
Polyclonal
Dilution:
Immunohistochemistry (Paraffin) Analysis : A 1:1,000 dilution from a representative lot detected Aquaporin 4 in rat cerebral cortex tissue.Western Blotting Analysis: A 1:500 dilution from a representative lot detected Aquaporin 4 in human brain tissue lysate.
Gene Alias:
AQP-4;Mercurial-insensitive water channel;MIWC
Host Species:
Rabbit
Molecular Weight of Antigen:
∽34.0 kDa observed; 34.48 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
25 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_001257487.1
Target Species:
Rat, Mouse, Human
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine, 150 mM NaCl (pH 7.4) with 0.05% sodium azide.
Gene Symbols:
Aqp4
Immunogen:
GST/HIs-taged recombinant fragment corresponding to 75 amino acids from the C-terminal region of rat Aquaporin-4.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antiody detects Aquaporin-4. It targets an epitope with in 75 amino acids from the C-terminal.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Antigen: __
Classification: __
Dilution: __
Gene Alias: __
Host Species: __
Molecular Weight of Antigen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Applications: __
Conjugate: __
Formulation: __
Gene Symbols: __
Immunogen: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Antigen:
__
Classification:
__
Dilution:
__
Gene Alias:
__
Host Species:
__
Molecular Weight of Antigen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Applications:
__
Conjugate:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Antigen: Myelin Basic Protein
Classification: Polyclonal
Dilution: __
Gene Alias: MBP
Host Species: Rabbit
Molecular Weight of Antigen: ∽17 kDa observed; 18.21 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): __
Target Species: Human, Rat
Applications: Western Blot, Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: MBP
Immunogen: KLH-conjugated linear peptide corresponding to 19 amino acids from the internal region of Guinea pig myelin basic protein.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects myelin basic protein. It targets an epitope within 19 amino acids from the internal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Antigen:
Myelin Basic Protein
Classification:
Polyclonal
Dilution:
__
Gene Alias:
MBP
Host Species:
Rabbit
Molecular Weight of Antigen:
∽17 kDa observed; 18.21 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
__
Target Species:
Human, Rat
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
MBP
Immunogen:
KLH-conjugated linear peptide corresponding to 19 amino acids from the internal region of Guinea pig myelin basic protein.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects myelin basic protein. It targets an epitope within 19 amino acids from the internal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Antigen: Myelin Basic Protein
Classification: Polyclonal
Dilution: __
Gene Alias: MBP
Host Species: Rabbit
Molecular Weight of Antigen: ∽17 kDa observed; 18.21 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 25 μg
Research Discipline: Neuroscience
Gene ID (Entrez): __
Target Species: Human, Rat
Applications: Western Blot, Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: MBP
Immunogen: KLH-conjugated linear peptide corresponding to 19 amino acids from the internal region of Guinea pig myelin basic protein.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects myelin basic protein. It targets an epitope within 19 amino acids from the internal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Antigen:
Myelin Basic Protein
Classification:
Polyclonal
Dilution:
__
Gene Alias:
MBP
Host Species:
Rabbit
Molecular Weight of Antigen:
∽17 kDa observed; 18.21 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
25 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
__
Target Species:
Human, Rat
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
MBP
Immunogen:
KLH-conjugated linear peptide corresponding to 19 amino acids from the internal region of Guinea pig myelin basic protein.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects myelin basic protein. It targets an epitope within 19 amino acids from the internal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.