ABC139225UG
PDGF-C, Rabbit anti-Human, Polyclonal, Millipore Sigma™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABC139225UG-Each-of-1 | In Stock | ₹ 16,643.00 |
ABC139225UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,643.00
GST (18%): ₹ 2,995.74
Total Price: ₹ 19,638.74
Antigen
PDGF-C
Classification
Polyclonal
Dilution
Western Blotting Analysis: A representative lot detected PDGF-C in Western Blotting applications (Hurst, N.J., et. al. (2012). Biochem J. 441(3):909-18).Western Blotting Analysis: A 1:2,000 dilution from a representative lot detected PDGF-C in HEK293T cells. (Courtesy of Hyeong-Reh Choi Kim lab at Wayne State University).
Gene Alias
Platelet-derived growth factor C;Fallotein;Spinal cord-derived growth factor;SCDGF;VEGF-E
Host Species
Rabbit
Molecular Weight of Antigen
∽48 kDa observed; 39.03 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity
25 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_057289
Target Species
Human
Form
Purified
Applications
Western Blot
Conjugate
Unconjugated
Formulation
Purified rabbit polyclonal antibody in PBS with 0.05% sodium azide.
Gene Symbols
PDGFC;SCDGE;UNQ174/PRO200
Immunogen
A linear peptide corresponding to 21 amino acids from the C-terminal growth factor domain of human Platelet-derived growth factor C (PDGF-C).
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This rabbit polyclonal antibody detects full length platelet derived growth factor C (PDGF-C) and also the 18 kDa growth factor domain.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Isotype
IgG
Related Products
Description
- Anti-PDGF-C, Cat
- No
- ABC1392, is a rabbit polyclonal antibody that detects Platelet-derived growth factor C and has been tested for use in Western Blotting
- Platelet-derived growth factor C (UniProt: Q9NRA1; also known as PDGF-C, Fallotein, Spinal cord-derived growth factor, SCDGF, VEGF-E) is encoded by the PDGFC (also known as SCDGE, UNQ174/PRO200) gene (Gene ID: 56034) in human
- PDGF-C is a disulfide-linked homodimeric growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis
- It also plays an important role in wound healing and angiogenesis
- It also serves as a potent mitogen and chemoattractant for cells of mesenchymal origin
- It is synthesized with a signal peptide (aa 1-22), which is subsequently cleaved off in the mature form
- Its CUB domain is localized to amino acids 46 to 163 and proteolytic removal of the CUB domain is essential for unmasking the receptor-binding epitopes of the core domain
- PDGF-C is expressed in the fallopian tube, vascular smooth muscle cells in kidney, breast and colon and in visceral smooth muscle of the gastrointestinal tract
- Highly expressed in retinal pigment epithelia
- Its high expression is also reported in retinal pigment epithelia
- In the kidney, it is constitutively expressed in parietal epithelial cells of Bowman's capsule, tubular epithelial cells, and in arterial endothelial cells
- Higher levels of PDGF-C and have been reported in the malignant breast tumor microenvironment
- In MCF-7 cells increased expression of PDGF-C is reported to enhance cell proliferation and tumor cell motility
- Tissue plasminogen activator and matriptase are shown to process PDGF-C in MCF-7 cells to its active form
- (Ref.: Hurst, NJ., et al
- (2012)
- Biochem
- J
- 441(3); 909-918; Lei, H., and Kazlauskas, A (2008)
- Exp
- Eye Res
- 86(5); 711-712).
Compare Similar Items
Show Difference
Antigen: PDGF-C
Classification: Polyclonal
Dilution: Western Blotting Analysis: A representative lot detected PDGF-C in Western Blotting applications (Hurst, N.J., et. al. (2012). Biochem J. 441(3):909-18).Western Blotting Analysis: A 1:2,000 dilution from a representative lot detected PDGF-C in HEK293T cells. (Courtesy of Hyeong-Reh Choi Kim lab at Wayne State University).
Gene Alias: Platelet-derived growth factor C;Fallotein;Spinal cord-derived growth factor;SCDGF;VEGF-E
Host Species: Rabbit
Molecular Weight of Antigen: ∽48 kDa observed; 39.03 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 25 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_057289
Target Species: Human
Form: Purified
Applications: Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in PBS with 0.05% sodium azide.
Gene Symbols: PDGFC;SCDGE;UNQ174/PRO200
Immunogen: A linear peptide corresponding to 21 amino acids from the C-terminal growth factor domain of human Platelet-derived growth factor C (PDGF-C).
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects full length platelet derived growth factor C (PDGF-C) and also the 18 kDa growth factor domain.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG
Antigen:
PDGF-C
Classification:
Polyclonal
Dilution:
Western Blotting Analysis: A representative lot detected PDGF-C in Western Blotting applications (Hurst, N.J., et. al. (2012). Biochem J. 441(3):909-18).Western Blotting Analysis: A 1:2,000 dilution from a representative lot detected PDGF-C in HEK293T cells. (Courtesy of Hyeong-Reh Choi Kim lab at Wayne State University).
Gene Alias:
Platelet-derived growth factor C;Fallotein;Spinal cord-derived growth factor;SCDGF;VEGF-E
Host Species:
Rabbit
Molecular Weight of Antigen:
∽48 kDa observed; 39.03 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
25 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_057289
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in PBS with 0.05% sodium azide.
Gene Symbols:
PDGFC;SCDGE;UNQ174/PRO200
Immunogen:
A linear peptide corresponding to 21 amino acids from the C-terminal growth factor domain of human Platelet-derived growth factor C (PDGF-C).
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects full length platelet derived growth factor C (PDGF-C) and also the 18 kDa growth factor domain.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG
Antigen: Pex14 (peroxisomal membrane marker)
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): NP_004556.1
Target Species: Human, Mouse, Rat
Form: Serum
Applications: Immunocytochemistry, Western Blot
Conjugate: Unconjugated
Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols: PEX14
Immunogen: His-tagged recombinant protein corresponding to human PEX14.
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C in undiluted aliquots for 12 months. Avoid repeated freeze/thaw cycles.
Isotype: __
Antigen:
Pex14 (peroxisomal membrane marker)
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
NP_004556.1
Target Species:
Human, Mouse, Rat
Form:
Serum
Applications:
Immunocytochemistry, Western Blot
Conjugate:
Unconjugated
Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols:
PEX14
Immunogen:
His-tagged recombinant protein corresponding to human PEX14.
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C in undiluted aliquots for 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
__
Antigen: UVRAG-FS mutant
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 100 μL
Research Discipline: Apoptosis and Cancer
Gene ID (Entrez): NP_003360
Target Species: Human
Form: Semi-purified
Applications: Western Blot, Immunoprecipitation
Conjugate: Unconjugated
Formulation: __
Gene Symbols: UVRAG
Immunogen: A frameshift (FS)-UVRAG derived linear peptide.
Purification Method: Ammonium Sulfate
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antibody targets an internal sequence in the N-terminal half and detects UVRAG-FS by Western blotting.
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: __
Antigen:
UVRAG-FS mutant
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
100 μL
Research Discipline:
Apoptosis and Cancer
Gene ID (Entrez):
NP_003360
Target Species:
Human
Form:
Semi-purified
Applications:
Western Blot, Immunoprecipitation
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
UVRAG
Immunogen:
A frameshift (FS)-UVRAG derived linear peptide.
Purification Method:
Ammonium Sulfate
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antibody targets an internal sequence in the N-terminal half and detects UVRAG-FS by Western blotting.
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
__
Antigen: PEX13 (peroxisomal membrane marker)
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): NP_002609.1
Target Species: Human, Mouse, Rat
Form: Serum
Applications: Western Blot
Conjugate: Unconjugated
Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols: PEX13
Immunogen: Recombinant protein corresponding to human PEX13 (peroxisomal membrane marker 13).
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: -20°C in undiluted aliquots for up to 12 months, Avoid Freeze/Thaw Cycles
Isotype: __
Antigen:
PEX13 (peroxisomal membrane marker)
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
NP_002609.1
Target Species:
Human, Mouse, Rat
Form:
Serum
Applications:
Western Blot
Conjugate:
Unconjugated
Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols:
PEX13
Immunogen:
Recombinant protein corresponding to human PEX13 (peroxisomal membrane marker 13).
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
-20°C in undiluted aliquots for up to 12 months, Avoid Freeze/Thaw Cycles
Isotype:
__