ABE86825UG
PGC-1 alpha, Rabbit anti-Mouse, Human, Polyclonal, Millipore Sigma™
Manufacturer: MilliporeSigma
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABE86825UG-Each-of-1 | In Stock | ₹ 16,456.61 |
ABE86825UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,456.61
GST (18%): ₹ 2,962.19
Total Price: ₹ 19,418.80
Antigen
PGC-1 alpha
Classification
Polyclonal
Dilution
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected PGC-1 alpha in A431, HUVEC, and NIH/3T3 cells.
Gene Alias
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha;PPAR-gamma coactivator 1-alpha;PPARGC-1-alpha
Host Species
Rabbit
Molecular Weight of Antigen
∽100 kDa observed; 90.59 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity
25 μg
Research Discipline
Epigenetics & Nuclear Function
Test Specificity
This rabbit polyclonal antibody detects PGC-1 alpha in human and murine adipose tissue. it targets an epitope within 21 amino acids from the C-terminus region.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Applications
Immunocytochemistry, Western Blot
Conjugate
Unconjugated
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
Ppargc1a;Pgc1;Pgc1a;Ppargc
Immunogen
KLH-conjugated linear peptide corresponding to 21 amino acids from the C-terminus region of murine PPAR-gamma coactivator 1-alpha.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Mouse, Human
Related Products
Description
- Anti-PGC-1 alpha, Cat
- No
- ABE868, is a highly specific rabbit polyclonal antibody that targets Peroxisome proliferator-activated receptor gamma coactivator 1-alpha and has been tested for use in Immunocytochemistry and Western Blotting
- Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (UniProt: O70343; also known as PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha) is encoded by the Ppargc1a (also known as Pgc1, Pgc1a, Ppargc1) gene (Gene ID: 19017) in murine species
- PGC-1 alpha is a member of a family of transcription coactivators that plays a central role in the regulation of cellular energy metabolism
- It is a homooligomeric transcriptional coactivator for steroid receptors and nuclear receptors that greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter
- It is expressed in muscles, liver, kidney, brown adipose tissue, heart, and brain
- It can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis and is also reported to play an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism
- PGC-1 alpha is known to induce the expression of PPARGC1- and ESRR-induced regulator, muscle 1 (PERM1) in the skeletal muscle in an estrogen-related receptors, -alpha (ESRRA)-dependent manner
- PGC-1 alpha is significantly induced in brown adipose tissue and skeletal muscle by exposure to cold and is also shown to be up-regulated in brown adipose tissue of obese leptin-deficient (ob/ob) and leptin-unresponsive (db/db) mice
- PGC-1 alpha is also required for oscillatory expression of clock genes, such as ARNTL/BMAL1 and NR1D1, through the co-activation of RORA and RORC, and metabolic genes, such as PDK4 and PEPCK.
Compare Similar Items
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Antigen: PGC-1 alpha
Classification: Polyclonal
Dilution: Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected PGC-1 alpha in A431, HUVEC, and NIH/3T3 cells.
Gene Alias: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha;PPAR-gamma coactivator 1-alpha;PPARGC-1-alpha
Host Species: Rabbit
Molecular Weight of Antigen: ∽100 kDa observed; 90.59 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 25 μg
Research Discipline: Epigenetics & Nuclear Function
Test Specificity: This rabbit polyclonal antibody detects PGC-1 alpha in human and murine adipose tissue. it targets an epitope within 21 amino acids from the C-terminus region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Immunocytochemistry, Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: Ppargc1a;Pgc1;Pgc1a;Ppargc
Immunogen: KLH-conjugated linear peptide corresponding to 21 amino acids from the C-terminus region of murine PPAR-gamma coactivator 1-alpha.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Human
Antigen:
PGC-1 alpha
Classification:
Polyclonal
Dilution:
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected PGC-1 alpha in A431, HUVEC, and NIH/3T3 cells.
Gene Alias:
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha;PPAR-gamma coactivator 1-alpha;PPARGC-1-alpha
Host Species:
Rabbit
Molecular Weight of Antigen:
∽100 kDa observed; 90.59 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
25 μg
Research Discipline:
Epigenetics & Nuclear Function
Test Specificity:
This rabbit polyclonal antibody detects PGC-1 alpha in human and murine adipose tissue. it targets an epitope within 21 amino acids from the C-terminus region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Immunocytochemistry, Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
Ppargc1a;Pgc1;Pgc1a;Ppargc
Immunogen:
KLH-conjugated linear peptide corresponding to 21 amino acids from the C-terminus region of murine PPAR-gamma coactivator 1-alpha.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Human
Antigen: CHD-3
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 100 μg
Research Discipline: __
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CHD3
Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of human CHD-3.
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Antigen:
CHD-3
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
100 μg
Research Discipline:
__
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CHD3
Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminus of human CHD-3.
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Antigen: JMJD8
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 100 μg
Research Discipline: __
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: JMJD8; C16orf20; PP14397
Immunogen: KLH-conjugated linear peptide corresponding to human JMJD8.
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Canine, Chimpanzee, Equine, Human, Porcine, Rhesus Monkey
Antigen:
JMJD8
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
100 μg
Research Discipline:
__
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
JMJD8; C16orf20; PP14397
Immunogen:
KLH-conjugated linear peptide corresponding to human JMJD8.
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Canine, Chimpanzee, Equine, Human, Porcine, Rhesus Monkey
Antigen: PRDM12
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 100 μg
Research Discipline: __
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Immunocytochemistry, Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: PRDM12; PFM9
Immunogen: KLH-conjugated linear peptide corresponding to human PRDM12.
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Antigen:
PRDM12
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
100 μg
Research Discipline:
__
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Immunocytochemistry, Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
PRDM12; PFM9
Immunogen:
KLH-conjugated linear peptide corresponding to human PRDM12.
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse