ABT1493AF48
MilliporeSigma™ Cofilin-1, Rabbit, Alexa Fluor 488, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABT1493AF48-Each-of-1 | In Stock | ₹ 40,197.80 |
ABT1493AF48 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,197.80
GST (18%): ₹ 7,235.604
Total Price: ₹ 47,433.404
Antigen
Cofilin-1
Classification
Polyclonal
Conjugate
Alexa Fluor 488
Gene
CFL, CFL1
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This Alexa Fluor™ 488-conjugated polyclonal antibody targets cofilin-1 N-terminal end sequence conserved among bovine, human, mouse, porcine, and rat species.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Immunocytochemistry
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody conjugate in PBS with 1.5% BSA and 0.05% Sodium Azide.
Gene Accession No.
P23528
Immunogen
KLH-conjugated linear peptide corresponding to the N-termnal end sequence of human cofilin-1.
Quantity
100 μL
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_005498
Target Species
Human
Form
Purified
Related Products
Description
- Cofilin-1 (UniProt P23528; also known as 18kDa phosphoprotein, Cofilin non-muscle isoform, p18) is encoded by the CFL1 (also known as CFL) gene (Gene ID 1072) in human
- Cofilin-1 (non-muscle cofilin), cofilin-2 (muscle cofilin), and actin-depolymerizing factor (ADF) play an essential role in regulating actin filament dynamics and reorganization by stimulating the severance and depolymerization of actin filaments
- The three cofilin family members share 70% to 81% sequence identity, exhibit similar biological functions, and display distinct but overlapping expression patterns
- Cofilins and ADF bind actin monomers and filaments (G-actin and F-actin) and increase the number of actin monomers and filament fragments, facilitating filament turnover and treadmilling at key locations in migrating cells
- Cofilins and ADF are inactivated by phosphorylation at Ser3 by LIM-kinases (LIMKs) and testicular protein kinases (TESKs) and are reactivated by dephosphorylation by the slingshot (SSH) family of protein phosphatases and chronophin
- Cfl1-knockout results in mouse embryonic lethality at E11.5 12.5 due to aberrant neural tube closure and defective neural crest cell migration, while Adf-deficient mice are viable with normal brain appearance, but suffer from corneal defects that cause blindness in adult mice.
Compare Similar Items
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Antigen: Cofilin-1
Classification: Polyclonal
Conjugate: Alexa Fluor 488
Gene: CFL, CFL1
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This Alexa Fluor™ 488-conjugated polyclonal antibody targets cofilin-1 N-terminal end sequence conserved among bovine, human, mouse, porcine, and rat species.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Immunocytochemistry
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody conjugate in PBS with 1.5% BSA and 0.05% Sodium Azide.
Gene Accession No.: P23528
Immunogen: KLH-conjugated linear peptide corresponding to the N-termnal end sequence of human cofilin-1.
Quantity: 100 μL
Research Discipline: Cell Structure
Gene ID (Entrez): NP_005498
Target Species: Human
Form: Purified
Antigen:
Cofilin-1
Classification:
Polyclonal
Conjugate:
Alexa Fluor 488
Gene:
CFL, CFL1
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This Alexa Fluor™ 488-conjugated polyclonal antibody targets cofilin-1 N-terminal end sequence conserved among bovine, human, mouse, porcine, and rat species.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Immunocytochemistry
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody conjugate in PBS with 1.5% BSA and 0.05% Sodium Azide.
Gene Accession No.:
P23528
Immunogen:
KLH-conjugated linear peptide corresponding to the N-termnal end sequence of human cofilin-1.
Quantity:
100 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_005498
Target Species:
Human
Form:
Purified
Antigen: Kinesin-like protein KIFC3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Immunofluorescence, Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to human Kinesin-like protein KIFC3.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_005541
Target Species: Human
Form: __
Antigen:
Kinesin-like protein KIFC3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Immunofluorescence, Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to human Kinesin-like protein KIFC3.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_005541
Target Species:
Human
Form:
__
Antigen: Dynamin related protein 1 (Drp1)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Immunocytochemistry, Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to the GSK3B interaction domain of mouse Dynamin related protein 1 (Drp1).
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_690029
Target Species: Human, Mouse, Ox, Rat, Rhesus Monkey
Form: __
Antigen:
Dynamin related protein 1 (Drp1)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Immunocytochemistry, Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to the GSK3B interaction domain of mouse Dynamin related protein 1 (Drp1).
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_690029
Target Species:
Human, Mouse, Ox, Rat, Rhesus Monkey
Form:
__
Antigen: RAB8A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of human RAB8A.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_005361
Target Species: Human
Form: __
Antigen:
RAB8A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminus of human RAB8A.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_005361
Target Species:
Human
Form:
__