AHB0042

Tau Monoclonal Antibody (TAU-5), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 AHB0042-Each-of-1 In Stock ₹ 38,502.00

AHB0042 - Each of 1

₹ 38,502.00

In Stock

Quantity

1

Base Price: ₹ 38,502.00

GST (18%): ₹ 6,930.36

Total Price: ₹ 45,432.36

Antigen

Tau

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

P10636, P10637, P19332, P29172

Gene Symbols

MAPT

Immunogen

Purified bovine microtubule-associated proteins.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Human, Mouse, Ovine, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

TAU-5

Conjugate

Unconjugated

Gene

MAPT

Gene Alias

AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

101121024, 17762, 281296, 29477, 4137

Content And Storage

-20°C

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA547404

--

Img

Invitrogen

AHB0061

--

Img

Thermo Scientific

01-676-579

--

Img

Thermo Scientific

71-109-0

--

Img

Invitrogen

50-138-27

--

Img

Novus Biologicals

NB274870A48

--

Img

Novus Biologicals

NB035834

--

Img

Novus Biologicals

NB274592A48

--

Description

  • Tau is a neuronal microtubule-associated protein found predominantly on axons
  • The function of Tau is to promote tubulin polymerization and stabilize microtubules
  • The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
  • Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
  • The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
  • In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
  • Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
  • Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
  • Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Compare Similar Items

Show Difference

Img

Invitrogen

AHB0042

--


Antigen:
Tau

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P10636, P10637, P19332, P29172

Gene Symbols:
MAPT

Immunogen:
Purified bovine microtubule-associated proteins.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Ovine, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
TAU-5

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
101121024, 17762, 281296, 29477, 4137

Content And Storage:
-20°C

Form:
Liquid

Img

Invitrogen

AHB0052

--


Antigen:
Oligomer A11

Classification:
Polyclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
P01308, P01322, P01325

Gene Symbols:
INS, Ins1

Immunogen:
Synthetic molecular mimic of soluble oligomers.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot, ELISA, Immunohistochemistry, Neutralization, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
INS

Gene Alias:
Antioligomer A11; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2-rs1; Insulin; insulin 1; Insulin A chain; Insulin B chain; insulin I; insulin-1; Insulin-1 A chain; Insulin-1 B chain; IRDN; MODY10; preproinsulin; proinsulin

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
16333, 24505, 3630

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

AHB0061

--


Antigen:
Tau (Cleaved Asp421, Asp422)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P10636, P10637, P19332

Gene Symbols:
MAPT

Immunogen:
KLH-CSSTGSIDMVD, corresponding to the C terminus of tau truncated at Asp421.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
TauC3

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
map tau; microtubules; neurofibrillary tangles

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17762, 29477, 4137

Content And Storage:
-20°C

Form:
Liquid

Img

Invitrogen

AHB0261

--


Antigen:
alpha Synuclein

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P37840

Gene Symbols:
SNCA

Immunogen:
Recombinant human alpha-synuclein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
Syn 211

Conjugate:
Unconjugated

Gene:
SNCA

Gene Alias:
Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
6622

Content And Storage:
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Form:
Liquid