AHP0012

Aggrecan Monoclonal Antibody (1R11 14A6), Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 AHP0012-Each-of-1 In Stock ₹ 39,015.36

AHP0012 - Each of 1

₹ 39,015.36

In Stock

Quantity

1

Base Price: ₹ 39,015.36

GST (18%): ₹ 7,022.765

Total Price: ₹ 46,038.125

Antigen

Aggrecan

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.5mg/mL sodium azide; pH 7.4

Gene Accession No.

P16112

Gene Symbols

ACAN

Immunogen

Human natural aggrecan (proteoglycan), purified from human articular cartilage.

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunohistochemistry, Western Blot

Clone

1R11 14A6

Conjugate

Unconjugated

Gene

ACAN

Gene Alias

ACAN; Agc; Agc1; AGCAN; aggrecan; aggrecan 1; aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122); aggrecan core protein; Aggrecan core protein 2; aggrecan CS2 domain; aggrecan epidermal growth factor-like domain-1; aggrecan G2 domain; aggrecan interglobular domain; aggrecan keratan sulfate domain; aggrecan, structural proteoglycan of cartilage; articular cartilage aggrecan precursor; b2b183Clo; cartilage aggregating proteoglycan; cartilage-specific proteoglycan core protein; Chondroitin sulfate proteoglycan 1; chondroitin sulfate proteoglycan core protein 1; cmd; CSPCP; CSPG1; CSPGCP; high density cartilage proteoglycan; large aggregating cartilage proteoglycan core protein; large aggregating proteoglycan; large aggregating proteoglycan, antigen; MSK16; SEDK

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

176

Content And Storage

4° C

Form

Liquid

Description

  • Purity is >95% by SDS-PAGE
  • This clone can also be referred to as clone number 1R1 14A6
  • Aggrecan also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1 is a protein that is encoded by the ACAN gene
  • The encoded protein is an integral part of the extracellular matrix in cartilaginous tissue and it withstands compression in cartilage
  • The human form of the protein is 2316 amino acids long (approximately 250 kDa) and can be expressed in multiple isoforms due to alternative splicing
  • Aggrecan exhibits a bottlebrush structure, in which chondroitin sulfate and keratan sulfate chains are attached to an extended protein core
  • The synthesis and degradation of aggrecan are being investigated for their roles in cartilage deterioration during joint injury, disease, and aging
  • It contains three interglobular domains (IGDs), G1, G2, and G3 that are involved in aggregation, hyaluronan binding, cell adhesion, and chondrocyte apoptosis
  • Aggrecan fragments from articular cartilage are released into the synovial fluid at all stages of human osteoarthritis as a result of cleavage by aggrecanase and MMP activity
  • Antibodies BC-3 and BC-4 can be used to detect these neo epitopes of Aggrecanase (ARGSVXXX) and MMP (XXXVDIPEN), respectively.

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Invitrogen

AHP0012

--


Antigen:
Aggrecan

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.5mg/mL sodium azide; pH 7.4

Gene Accession No.:
P16112

Gene Symbols:
ACAN

Immunogen:
Human natural aggrecan (proteoglycan), purified from human articular cartilage.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
1R11 14A6

Conjugate:
Unconjugated

Gene:
ACAN

Gene Alias:
ACAN; Agc; Agc1; AGCAN; aggrecan; aggrecan 1; aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122); aggrecan core protein; Aggrecan core protein 2; aggrecan CS2 domain; aggrecan epidermal growth factor-like domain-1; aggrecan G2 domain; aggrecan interglobular domain; aggrecan keratan sulfate domain; aggrecan, structural proteoglycan of cartilage; articular cartilage aggrecan precursor; b2b183Clo; cartilage aggregating proteoglycan; cartilage-specific proteoglycan core protein; Chondroitin sulfate proteoglycan 1; chondroitin sulfate proteoglycan core protein 1; cmd; CSPCP; CSPG1; CSPGCP; high density cartilage proteoglycan; large aggregating cartilage proteoglycan core protein; large aggregating proteoglycan; large aggregating proteoglycan, antigen; MSK16; SEDK

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
176

Content And Storage:
4° C

Form:
Liquid

Img

Invitrogen

AHR0061

--


Antigen:
IL-6 Receptor

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
P08887

Gene Symbols:
IL6R

Immunogen:
CHO cells transfected with cDNA corresponding to the gp80 IL-6 receptor gene.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Neutralization

Clone:
B-R6

Conjugate:
Unconjugated

Gene:
IL6R

Gene Alias:
CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
3570

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

AHR0221

--


Antigen:
INSR alpha

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P06213

Gene Symbols:
INSR

Immunogen:
IM-9 lymphocytes followed by purified insulin receptor.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Ovine, Porcine

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
ELISA, Functional Assay, Immunocytochemistry, Immunoprecipitation, Inhibition Assays, Western Blot

Clone:
83-14

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3643, 396755, 408017, 443431

Content And Storage:
4° C

Form:
Liquid

Img

Invitrogen

AHR0231

--


Antigen:
INSR alpha

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P06213

Gene Symbols:
INSR

Immunogen:
IM-9 lymphocytes followed by purified insulin receptor.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Ovine, Porcine, Rabbit

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
83-7

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100008911, 3643, 396755, 408017, 443431

Content And Storage:
4° C

Form:
Liquid