AMPA6842
Caspase 9 Monoclonal Antibody (LAP6 96-2-22), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | AMPA6842-Each-of-1 | In Stock | ₹ 50,352.06 |
AMPA6842 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,352.06
GST (18%): ₹ 9,063.371
Total Price: ₹ 59,415.431
Antigen
Caspase 9
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P55211
Gene Symbols
CASP9
Immunogen
Recombinant human Caspase 9 pro-domain protein.
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
LAP6 96-2-22
Conjugate
Unconjugated
Gene
CASP9
Gene Alias
25 kDa caspase-9 dominant negative protein; AI115399; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; AW493809; cas9; CASP 9; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase9; caspase-9; caspase-9 dominant negative form; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; caspase-9-carboxyl-terminal divergent; CTD; Ice-Lap6; ICE-like apoptotic protease 6; Mch6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
842
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Suggested positive control: HEK 293 whole cell lysate
- Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that contains a CARD domain
- Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates
- Caspase 9 is active as a heterotetramer, is present in the cytosol and, upon activation, translocates to the mitochondria
- Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6
- Further, Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution
- Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3
- Caspase 9 promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, and proteolytically cleaves poly(ADP- ribose) polymerase (PARP)
- Caspase 9 is expressed in variety of human tissues
- An isoform of rat Caspase-9 has been identified in which the C terminus of full-length Caspase-9 is replaced with an alternative peptide sequence
- Mutations in Caspase 9 affect brain development
- In mice, insufficient Caspase 9 have resulted in abnormal cerebrum development and neuron development
- In humans, dysfunctional Caspase 9 expression vary from tissue to tissue
- Low levels of Caspase 9 may play a role in cancer development and neurodegenerative diseases such as Alzheimer’s Disease (AD).
Compare Similar Items
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Antigen: Caspase 9
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P55211
Gene Symbols: CASP9
Immunogen: Recombinant human Caspase 9 pro-domain protein.
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: LAP6 96-2-22
Conjugate: Unconjugated
Gene: CASP9
Gene Alias: 25 kDa caspase-9 dominant negative protein; AI115399; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; AW493809; cas9; CASP 9; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase9; caspase-9; caspase-9 dominant negative form; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; caspase-9-carboxyl-terminal divergent; CTD; Ice-Lap6; ICE-like apoptotic protease 6; Mch6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 842
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Caspase 9
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P55211
Gene Symbols:
CASP9
Immunogen:
Recombinant human Caspase 9 pro-domain protein.
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
LAP6 96-2-22
Conjugate:
Unconjugated
Gene:
CASP9
Gene Alias:
25 kDa caspase-9 dominant negative protein; AI115399; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; AW493809; cas9; CASP 9; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase9; caspase-9; caspase-9 dominant negative form; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; caspase-9-carboxyl-terminal divergent; CTD; Ice-Lap6; ICE-like apoptotic protease 6; Mch6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
842
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: CAF1 p60
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.1% sodium azide
Gene Accession No.: Q13112
Gene Symbols: Chaf1b
Immunogen: Recombinant human CAF-1p60
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: SS 53
Conjugate: Unconjugated
Gene: Chaf1b
Gene Alias: 2600017H24Rik; C76145; CAF1; CAF-1; CAF1 p60; CAF-1 subunit B; CAF1A; CAF1P60; CAF-I 60 kDa subunit; CAF-I p60; CAF-Ip60; CHAF1B; Chromatin assembly factor 1 subunit B; chromatin assembly factor 1, subunit B; chromatin assembly factor 1, subunit B (p60); chromatin assembly factor I p60 subunit; fe36g06; gef; human chromatin assembly factor-I p60 subunit; LOW QUALITY PROTEIN: chromatin assembly factor 1 subunit B; M-phase phosphoprotein 7; MPHOSPH7; MPP7; p60 CAF1; p60-CAF1; wu:fd07c09; wu:fe36g06; wu:fv38g09; zgc:56096
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 8208
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Antigen:
CAF1 p60
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.1% sodium azide
Gene Accession No.:
Q13112
Gene Symbols:
Chaf1b
Immunogen:
Recombinant human CAF-1p60
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
SS 53
Conjugate:
Unconjugated
Gene:
Chaf1b
Gene Alias:
2600017H24Rik; C76145; CAF1; CAF-1; CAF1 p60; CAF-1 subunit B; CAF1A; CAF1P60; CAF-I 60 kDa subunit; CAF-I p60; CAF-Ip60; CHAF1B; Chromatin assembly factor 1 subunit B; chromatin assembly factor 1, subunit B; chromatin assembly factor 1, subunit B (p60); chromatin assembly factor I p60 subunit; fe36g06; gef; human chromatin assembly factor-I p60 subunit; LOW QUALITY PROTEIN: chromatin assembly factor 1 subunit B; M-phase phosphoprotein 7; MPHOSPH7; MPP7; p60 CAF1; p60-CAF1; wu:fd07c09; wu:fe36g06; wu:fv38g09; zgc:56096
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
8208
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Antigen: DIABLO
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.1% sodium azide
Gene Accession No.: Q9JIQ3, Q9NR28
Gene Symbols: DIABLO
Immunogen: Recombinant mature human Smac/DIABLO (lacks amino acids 1-55 present in Smac/DIABLO precursor)
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1, IgG3
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 78-1-118
Conjugate: Unconjugated
Gene: DIABLO
Gene Alias: 0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; Smac; Smac protein; SMAC3
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 288753, 56616, 66593
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
DIABLO
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.1% sodium azide
Gene Accession No.:
Q9JIQ3, Q9NR28
Gene Symbols:
DIABLO
Immunogen:
Recombinant mature human Smac/DIABLO (lacks amino acids 1-55 present in Smac/DIABLO precursor)
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1, IgG3
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
78-1-118
Conjugate:
Unconjugated
Gene:
DIABLO
Gene Alias:
0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; Smac; Smac protein; SMAC3
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
288753, 56616, 66593
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Survivin
Classification: Monoclonal
Concentration: 1.9 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O15392
Gene Symbols: Birc5
Immunogen: Recombinant human survivin, full-length
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Hamster, Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 32.1
Conjugate: Unconjugated
Gene: Birc5
Gene Alias: AAC-11; AP14; Api4; apoptosis inhibitor 4; Apoptosis inhibitor survivin; baculoviral IAP repeat containing 5; baculoviral IAP repeat-containing 5; baculoviral IAP repeat-containing 5 (survivin); baculoviral IAP repeat-containing protein 5; BIRC 5; BIRC5; EPR 1; EPR-1; Iap4; inhibitor of apoptosis; survivin; survivin variant 3 alpha; survivin40; SVV; TIAP
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100689366, 332
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Survivin
Classification:
Monoclonal
Concentration:
1.9 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O15392
Gene Symbols:
Birc5
Immunogen:
Recombinant human survivin, full-length
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Hamster, Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
32.1
Conjugate:
Unconjugated
Gene:
Birc5
Gene Alias:
AAC-11; AP14; Api4; apoptosis inhibitor 4; Apoptosis inhibitor survivin; baculoviral IAP repeat containing 5; baculoviral IAP repeat-containing 5; baculoviral IAP repeat-containing 5 (survivin); baculoviral IAP repeat-containing protein 5; BIRC 5; BIRC5; EPR 1; EPR-1; Iap4; inhibitor of apoptosis; survivin; survivin variant 3 alpha; survivin40; SVV; TIAP
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100689366, 332
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid