APP4699

Synaptotagmin 1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 APP4699-Each-of-1 In Stock ₹ 47,015.22

APP4699 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

Synaptotagmin 1

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P21707, P46096

Gene Symbols

Syt1

Immunogen

Synthetic peptide corresponding to amino acid residues specific to rat synaptotagmin 1 conjugated to KLH

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

Syt1

Gene Alias

AW124717; DKFZp781D2042; FLJ42519; G630098F17Rik; P65; SV DKFZp781D2042; SV SYT; svp65; Syb1; synaptotagmin 1; synaptotagmin 1 L homeolog; synaptotagmin 2; synaptotagmin I; synaptotagmin I protein; synaptotagmin I variant b; Synaptotagmin II; Synaptotagmin XI; synaptotagmin-1; Synaptotagmin-2; SYT; Syt1; syt1.L; SYT2; SytI; SytII; XELAEV_18022019mg

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20979, 25716

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • This antibody is predicted to react with human, mouse, bovine, chicken and non-human primate based on 100% sequence homology
  • In Western blot, this antibody is specific for ∽65 kDa synaptotagmin I protein
  • Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release
  • Studies indicate that synaptotagmin’s Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane
  • It has been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size
  • Synaptotagmin 1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse
  • Further, Synaptotagmin 1 binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone
  • A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has been reported
  • Synaptotagmin 1 can also bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2
  • Diseases associated with the dysfunction of Synaptotagmin 1 include food-borne botulism and infant botulism.

Compare Similar Items

Show Difference

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Thermo Scientific

APP4699

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Antigen:
Synaptotagmin 1

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P21707, P46096

Gene Symbols:
Syt1

Immunogen:
Synthetic peptide corresponding to amino acid residues specific to rat synaptotagmin 1 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
Syt1

Gene Alias:
AW124717; DKFZp781D2042; FLJ42519; G630098F17Rik; P65; SV DKFZp781D2042; SV SYT; svp65; Syb1; synaptotagmin 1; synaptotagmin 1 L homeolog; synaptotagmin 2; synaptotagmin I; synaptotagmin I protein; synaptotagmin I variant b; Synaptotagmin II; Synaptotagmin XI; synaptotagmin-1; Synaptotagmin-2; SYT; Syt1; syt1.L; SYT2; SytI; SytII; XELAEV_18022019mg

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20979, 25716

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

APP7259

--


Antigen:
Streptococcus pneumoniae

Classification:
Polyclonal

Formulation:
PBS with 0.1% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Whole cell blend of numerous serotypes.

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Pneumococcus; s pneumoniae; S. pneumoniae

Host Species:
Rabbit

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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APP767A

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Antigen:
VAMP3

Classification:
Polyclonal

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P63024, P63025, Q15836

Gene Symbols:
VAMP3

Immunogen:
Sythetic peptide corresponding to residues M(1) S T G V P S G S S A A T G S N R R(18) C of mouse VAMP-3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
VAMP3

Gene Alias:
CEB; Cellubrevin; D130027G05Rik; hypothetical protein LOC415163; Syb3; Synaptobrevin-3; vamp; Vamp3; VAMP-3; vesicle associated membrane protein 3; vesicle-associated membrane protein 3; vesicle-associated membrane protein 3 (cellubrevin); zgc:86726

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22319, 29528, 9341

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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APPA6505

--


Antigen:
OGG1

Classification:
Polyclonal

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O08760, O15527, O70249

Gene Symbols:
OGG1

Immunogen:
A peptide derived from the human Ogg1 (within amino acids 1-100).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
OGG1

Gene Alias:
8-hydroxyguanine DNA glycosylase; 8-oxoguanine DNA glycosylase; 8-oxoguanine DNA-glycosylase 1; 8-oxoguanine-DNA-glycosylase; AP lyase; DNA-(apurinic or apyrimidinic site) lyase; DNA-apurinic or apyrimidinic site lyase; HMMH; HOGG1; Mmh; MUTM; N-glycosylase/DNA lyase; OGG1; OGG1 type 1f; OGH1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100155036, 103345505, 18294, 4968, 81528

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid