BDB553655

CD154 Hamster anti-Mouse, NA/LE, Unlabeled, Clone: MR1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB553655-Each-of-1 In Stock ₹ 34,052.88

BDB553655 - Each of 1

₹ 34,052.88

In Stock

Quantity

1

Base Price: ₹ 34,052.88

GST (18%): ₹ 6,129.518

Total Price: ₹ 40,182.398

Antigen

CD154

Classification

Monoclonal

Concentration

1.0mg/mL

Description

CD40 Ligand; CD40L; gp39; Ly-62; Tnfsf5; T-BAM; HIGM1; IMD3

Host Species

Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

MR1

Conjugate

Unconjugated

Formulation

No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen

Activated mouse Th1 clone D1.6

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG κ3

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Description

  • The MR1 antibody reacts with CD154 (CD40 Ligand, gp39), an accessory molecule expressed on activated T helper (CD4+) lymphocytes
  • CD154 has also been detected on other types of leukocytes, including CD8+ T cells, medullary thymocytes, activated CD4+ NK-T cells, and human NK cells
  • CD154 plays an important role in costimulatory interactions between T and B lymphocytes and between antigen-presenting cells and lymphocytes, regulating the immune response at multiple levels
  • MR1 mAb inhibits in vitro activation of B lymphocytes by T helper cells by blocking interaction of gp39 with CD40
  • In vitro interactions of T cells and antigen-presenting cells can also be blocked by the MR1 antibody
  • In vivo treatment with MR1 antibody blocks the development of experimental autoimmune disease, inhibits formation of germinal centers and generation of memory B cells, reduces T-lymphocyte responses to allogeneic cells and allografts, prevents intrathymic deletion of self-reactive T lymphocytes, and disrupts antigen-specific T-cell responses.

Compare Similar Items

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BD Biosciences

BDB553655

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Antigen:
CD154

Classification:
Monoclonal

Concentration:
1.0mg/mL

Description:
CD40 Ligand; CD40L; gp39; Ly-62; Tnfsf5; T-BAM; HIGM1; IMD3

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Flow Cytometry

Clone:
MR1

Conjugate:
Unconjugated

Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen:
Activated mouse Th1 clone D1.6

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG κ3

Img

BD Biosciences

BDB553656

--


Antigen:
CD154

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
CD40 Ligand, gp39

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Flow Cytometry

Clone:
MR1

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Activated mouse Th1 clone D1.6

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG κ3

Img

Fischer Scientific

BDB553658

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Antigen:
CD154

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
CD40 Ligand, gp39

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
MR1

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Activated mouse Th1 clone D1.6

Quantity:
0.2 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG κ3

Img

BD Biosciences

BDB553663

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Antigen:
Vβ 8.3 T-Cell Receptor

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
__

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
1B3.3

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Vβ 8.3 TCR-expressing mouse Th1 clone 3.L2

Quantity:
0.25 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG3