BDB554274
Disialoganglioside GD3 Mouse anti-Human, Unlabeled, Clone: MB3.6, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB554274-Each-of-1 | In Stock | ₹ 29,389.86 |
BDB554274 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,389.86
GST (18%): ₹ 5,290.175
Total Price: ₹ 34,680.035
Antigen
Disialoganglioside GD3
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
FM9 human melamona cell line
Quantity
0.1 mg
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG3 κ
Applications
Flow Cytometry
Clone
MB3.6
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- Gangliosides are sialic-acid bearing glycolipids expressed on the surface of all mammalian cells, and are likely involved in mediating cell-substratum interactions
- They are important target antigens for antibody mediated cytolysis of human melanoma and neuroblastoma cells
- Human melanoma cells produce gangliosides GD2 and/or GD3 which are present in substratum-attached material, and may play a significant role in the melanoma metastatic phenotype
- Ganglioside GD3 is a major surface marker on most human melanoma cells
- MB3.6 has been used to localize GD3 in the plasma membrane and in focal adhesion plaques of human melanoma cells
- Clone MB3.6 has also been shown to lyse GD3 positive human melanoma cells by both antibodydependent and complement-mediated cytotoxicity, and to inhibit the growth of human melanoma cells in athymic nude mice
- Clone MB3.6 specifically reacts with human GD3 ganglioside
- It does not cross-react with a variety of other gangliosides purified from melanoma or neuroblastoma cells
- The FM9 human melanoma cell line was used as the immunogen
- Host Species: Mouse Clone: MB3.6 Isotype: IgG3, κ Species Reactivity: Human Immunogen: FM9 human melamona cell line Flow Cytometry, Functional Assay, Immunofluorescence, Immunohistochemistry (Frozen)
Compare Similar Items
Show Difference
Antigen: Disialoganglioside GD3
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: FM9 human melamona cell line
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG3 κ
Applications: Flow Cytometry
Clone: MB3.6
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
Disialoganglioside GD3
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
FM9 human melamona cell line
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG3 κ
Applications:
Flow Cytometry
Clone:
MB3.6
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: Chondroitin Sulfate
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human Melanoma Cells
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG2a
Applications: Flow Cytometry
Clone: 9.2.27
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
Chondroitin Sulfate
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human Melanoma Cells
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG2a
Applications:
Flow Cytometry
Clone:
9.2.27
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: PDGF-AB/BB
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human PDGF BB Recombinant Protein
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Applications: Western Blot
Clone: SIS1
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
PDGF-AB/BB
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human PDGF BB Recombinant Protein
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1
Applications:
Western Blot
Clone:
SIS1
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: JNK1/JNK2
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human JNK1 Fusion Protein
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG2a
Applications: Western Blot
Clone: G151-666
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
JNK1/JNK2
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human JNK1 Fusion Protein
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG2a
Applications:
Western Blot
Clone:
G151-666
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C