BDB555286

CD70 Rat anti-Mouse, PE, Clone: FR70, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB555286-Each-of-1 In Stock ₹ 22,074.48

BDB555286 - Each of 1

₹ 22,074.48

In Stock

Quantity

1

Base Price: ₹ 22,074.48

GST (18%): ₹ 3,973.406

Total Price: ₹ 26,047.886

Antigen

CD70

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

BALB/c mouse B lymphoma A202J

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

FR70

Conjugate

PE

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The FR70 monoclonal antibody specifically binds to mouse CD70, a 30-33-kDa type-II transmembrane glycoprotein belonging to the TNF/NGF superfamily
  • CD70 is the ligand for CD27 and is expressed primarily on activated B cells
  • CD70 expression can be induced by activation of splenocytes with lipopolysaccharide and stimulatory antibodies specific for IgM, CD40 or both
  • mRNA coding for CD70 is transiently expressed after Concanavalin A stimulation of splenocytes or thymocytes
  • CD70 has been observed to be expressed on dendritic cells of Leishmania major-infected mice
  • The CD27-CD70 interaction delivers costimulatory signals to T cells and NK cells
  • It has been reported that FR70 antibody blocks binding of mCD27-Ig fusion protein to mouse Cd70-transfected cells and inhibits some in vitro T-cell- and NK-cell-dependent responses
  • R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae
  • It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule
  • This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.

Compare Similar Items

Show Difference

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BD Biosciences

BDB555286

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Antigen:
CD70

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
BALB/c mouse B lymphoma A202J

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
FR70

Conjugate:
PE

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB555288

--


Antigen:
CD127

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse CD127-human IgG fusion protein

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2a λ

Applications:
Flow Cytometry

Clone:
B12-1

Conjugate:
Biotin

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB555290

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Antigen:
CD178

Classification:
Monoclonal

Concentration:
1.0mg/mL

Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen:
Mouse FasL-transfected cells

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
MFL3

Conjugate:
Unconjugated

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Img

BD Biosciences

BDB555291

--


Antigen:
CD178

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse FasL-transfected cells

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
MFL3

Conjugate:
Unconjugated

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C