BDB558134
Btk (pY551) & Itk (pY511) Mouse anti-Human, Alexa Fluor 647, Clone: 24A/BTK (Y551), BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558134-Each-of-1 | In Stock | ₹ 29,560.98 |
BDB558134 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,560.98
GST (18%): ₹ 5,320.976
Total Price: ₹ 34,881.956
Antigen
Btk (pY551) & Itk (pY511)
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
24A/BTK (Y551)
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Phosphorylated Human Btk Peptide
Quantity
50 Tests
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1 κ
Description
- B ruton's t yrosine k inase (Btk) is a nonreceptor tyrosine kinase whose function is critical for proper B cell development and signaling
- The activity of Btk is regulated by Src mediated phosphorylation of the kinase domain at tyrosine 551 (Y551)
- This event induces Btk kinase activity and subsequent autophosphorylation at Y223
- Phosphorylated Btk then associates with the cell membrane via the interaction of the PH domain with phosphatidylinositol 3, 4, 5-triphosphate
- γ1 (PLC γ1), a key regulator of calcium mobilization and extracellular signal-regulated kinase (ERK) activation
- Itk is regulated by an activating transphosphorylation event in which Y511 in the kinase domain is phosphorylated by Lck
- The 24a/BTK (Y551) monoclonal antibody recognizes the Y551-phosphorylated form of human Btk and the Y511 phosphorylated form of human Itk.
Compare Similar Items
Show Difference
Antigen: Btk (pY551) & Itk (pY511)
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 24A/BTK (Y551)
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Btk Peptide
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Antigen:
Btk (pY551) & Itk (pY511)
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
24A/BTK (Y551)
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Btk Peptide
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Stat4 (pY693)
Classification: Monoclonal
Conjugate: Alexa Fluor 488
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 38/P-STAT4
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Stat4 (pY693)
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG2b κ
Antigen:
Stat4 (pY693)
Classification:
Monoclonal
Conjugate:
Alexa Fluor 488
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
38/P-STAT4
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Stat4 (pY693)
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG2b κ
Antigen: Stat4 (pY693)
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 38/P-STAT4
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Stat4 (pY693)
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG2b κ
Antigen:
Stat4 (pY693)
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
38/P-STAT4
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Stat4 (pY693)
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG2b κ
Antigen: GITR
Classification: Monoclonal
Conjugate: FITC
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: DTA-1
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse CD25+ CD4+ T Cell Line
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2b
Antigen:
GITR
Classification:
Monoclonal
Conjugate:
FITC
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
DTA-1
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse CD25+ CD4+ T Cell Line
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2b