BDB558524
EGF Receptor (pY1173) Mouse, Alexa Fluor 647, Clone: 9H2, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558524-Each-of-1 | In Stock | ₹ 28,257.50 |
BDB558524 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,257.50
GST (18%): ₹ 5,086.35
Total Price: ₹ 33,343.85
Antigen
EGF Receptor (pY1173)
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
9H2
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Phosphorylated Human EGF Receptor Peptide
Quantity
50 Tests
Research Discipline
Cell Biology
Target Species
Canine, Human, Mouse, Rat
Isotype
IgG1 κ
Description
- Epidermal Growth Factor (EGF) elicits a variety of cellular responses that are initiated by EGF Receptor (EGFR) binding and activation of intrinsic tyrosine kinase activity
- EGFR, also known as ErbB1 or HER1, is a member of the ErbB class of receptor protein tyrosine kinases
- It has an extracellular ligand-binding domain, a single transmembrane region, and a cytoplasmic region containing a protein tyrosine kinase domain and a c-terminal regulatory domain with many phosphorylation sites
- Following ligand binding, EGFR forms homodimers and heterodimers with ErbB2
- Specific C-terminal tyrosine residues are then autophosphorylated and, in turn, bind to adaptor proteins, kinases, or protein tyrosine phosphatases
- Specifically, phosphorylated tyrosine 1173 (Y1173) interacts with Shc, SHP1, and PLCγ, which mediate downstream signaling cascades and negative feedback regulation of EGFR activation
- Inappropriate expression or mutations of EGFR and/or deregulation of its signaling pathways are associated with many types of cancer, making EGFR a promising target for cancer therapies
- The 9H2 monoclonal antibody recognizes the phosphorylated Y1173 in the regulatory domain of human EGFR
- Intracellular Staining
Compare Similar Items
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Antigen: EGF Receptor (pY1173)
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 9H2
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human EGF Receptor Peptide
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Canine, Human, Mouse, Rat
Isotype: IgG1 κ
Antigen:
EGF Receptor (pY1173)
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
9H2
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human EGF Receptor Peptide
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Canine, Human, Mouse, Rat
Isotype:
IgG1 κ
Antigen: Btk
Classification: Monoclonal
Conjugate: PE
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 53/BTK
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human N-terminal Btk Recombinant Protein
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG2a
Antigen:
Btk
Classification:
Monoclonal
Conjugate:
PE
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
53/BTK
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human N-terminal Btk Recombinant Protein
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG2a
Antigen: Btk
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 53/BTK
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human N-terminal Btk Recombinant Protein
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG2a
Antigen:
Btk
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
53/BTK
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human N-terminal Btk Recombinant Protein
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG2a
Antigen: CD205
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Flow Cytometry
Clone: MG38
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: __
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Human
Isotype: IgG2b
Antigen:
CD205
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Flow Cytometry
Clone:
MG38
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
__
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG2b