BDB561272

CD279 Mouse anti-Human, PE-Cy7, Clone: EH12.1 (also known as EH12), BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB561272-Each-of-1 In Stock ₹ 33,539.52

BDB561272 - Each of 1

₹ 33,539.52

In Stock

Quantity

1

Base Price: ₹ 33,539.52

GST (18%): ₹ 6,037.114

Total Price: ₹ 39,576.634

Antigen

CD279

Classification

Monoclonal

Conjugate

PE-Cyanine7

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human PD-1 Recombinant Protein

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

EH12.1 (also known as EH12)

Description

hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The EH12.1 monoclonal antibody specifically binds to CD279
  • CD279 is an immunoregulatory receptor that is expressed on activated T cells, B cells and myeloid cells and contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region
  • Mice deficient in CD279 show a breakdown of peripheral tolerance and manifest multiple autoimmune symptoms
  • PD-L1 and PD-L2 are ligands of CD279 and are members of the B7 gene family
  • Interaction of CD279:PD-Ligands results in inhibition of T cell proliferation and cytokine secretion
  • Reports suggest that the B7/CTLA-4 pathway functions primarily to attenuate, limit, and/or terminate naοve T-cell activation in secondary lymphoid organs
  • The PD-ligand:CD279 pathway, on the other hand, may primarily attenuate, limit, and/or terminate T-, B-, and myeloid cell activation/effector function at sites of inflammation in the periphery.

Compare Similar Items

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BD Biosciences

BDB561272

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Antigen:
CD279

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human PD-1 Recombinant Protein

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
EH12.1 (also known as EH12)

Description:
hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB561273

--


Antigen:
CD279 (PD-1)

Classification:
Monoclonal

Conjugate:
PerCP-Cyanine5.5

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human PD-1 Recombinant Protein

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
EH12.1 (also known as EH12)

Description:
hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB561277

--


Antigen:
Ki-67

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Human Ki-67

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
B56

Description:
MKI67; Antigen identified by monoclonal antibody Ki-67; KIA

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat, Rhesus Monkey

Isotype:
IgG1 κ

Img

BD Biosciences

BDB561278

--


Antigen:
MIP-1b

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Recombinant Human MIP-1β

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
D21-1351

Description:
Macrophage inflammatory protein 1-beta; CCL4; C-C motif chemokine 4; LAG-1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ