BDB562073
Stat4 (pY693) Mouse, PE, Clone: 38/P-STAT4, BD
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562073-Each-of-1 | In Stock | ₹ 1,22,350.80 |
BDB562073 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,22,350.80
GST (18%): ₹ 22,023.144
Total Price: ₹ 1,44,373.944
Antigen
Stat4 (pY693)
Classification
Monoclonal
Conjugate
PE
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen
Phosphorylated Human Stat4 (pY693)
Quantity
250 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
38/P-STAT4
Description
Signal transducer and activator of transcription 4; SLEB11
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human, Mouse
Isotype
IgG2b κ
Related Products
Description
- The Stat proteins function both as cytoplasmic signal transducers and as activators of transcription
- Seven mammalian Stat proteins have been identified: Stat1-4, Stat5a, 5b, and Stat6
- Stat4 has been shown to play an important role in development of T helper cells, specifically the Th1 subset
- Stat4 is activated by IL-12 and by type 1 interferons
- Knockout mice supported the role that Stat4 plays in IL-12 signaling because lymphocytes from Stat 4-/- mice could neither differentiate into Th1 cells nor produce IFN-γ in response to treatment with IL-12
- IFN-γ plays an important role in host defense
- A key component in the activation of Stat4 is the phosphorylation on tyrosine and serine residues in response to IL-12 stimulation
- IL-12 stimulation leads to the phosphorylation of Stat4 on tyrosine 693 and serine 721
- Transcriptional activity of Stat4 has been shown to be significantly reduced when residues Y693 and S721 are mutated.
Compare Similar Items
Show Difference
Antigen: Stat4 (pY693)
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Stat4 (pY693)
Quantity: 250 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 38/P-STAT4
Description: Signal transducer and activator of transcription 4; SLEB11
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Isotype: IgG2b κ
Antigen:
Stat4 (pY693)
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Stat4 (pY693)
Quantity:
250 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
38/P-STAT4
Description:
Signal transducer and activator of transcription 4; SLEB11
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Isotype:
IgG2b κ
Antigen: Stat5
Classification: Monoclonal
Conjugate: Alexa Fluor 488
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Phosphorylated Stat5 Peptide
Quantity: 250 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry (Intracellular Staining)
Clone: 47/Stat5
Description: Signal transducer and activator of transcription 5; MGF; MPF
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Mouse, Rat, Sheep
Isotype: IgG1 κ
Antigen:
Stat5
Classification:
Monoclonal
Conjugate:
Alexa Fluor 488
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Phosphorylated Stat5 Peptide
Quantity:
250 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry (Intracellular Staining)
Clone:
47/Stat5
Description:
Signal transducer and activator of transcription 5; MGF; MPF
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat, Sheep
Isotype:
IgG1 κ
Antigen: Stat5 (pY694)
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Phosphorylated Stat5 Peptide
Quantity: 250 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 47/Stat5(pY694)
Description: Signal transducer and activator of transcription 5; MGF; MPF
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Mouse, Rat, Sheep
Isotype: IgG1 κ
Antigen:
Stat5 (pY694)
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Phosphorylated Stat5 Peptide
Quantity:
250 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
47/Stat5(pY694)
Description:
Signal transducer and activator of transcription 5; MGF; MPF
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat, Sheep
Isotype:
IgG1 κ
Antigen: Stat6 (pY641)
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Stat6 (pY641)
Quantity: 250 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 18/P-STAT6
Description: Signal transducer and activator of transcription 6; IL-4 Stat
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a
Antigen:
Stat6 (pY641)
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Stat6 (pY641)
Quantity:
250 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
18/P-STAT6
Description:
Signal transducer and activator of transcription 6; IL-4 Stat
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a