BDB562499

CD95 Hamster anti-Mouse, PE-CF594, Clone: Jo2, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB562499-Each-of-1 In Stock ₹ 35,079.60

BDB562499 - Each of 1

₹ 35,079.60

In Stock

Quantity

1

Base Price: ₹ 35,079.60

GST (18%): ₹ 6,314.328

Total Price: ₹ 41,393.928

Antigen

CD95

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Apo-1; Apt1; Fas; FASLG receptor; lpr; TNFR6; Tnfrsf6; TNR6

Host Species

Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2

Applications

Flow Cytometry

Clone

Jo2

Conjugate

PE-CF594

Formulation

Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen

WR19L mouse lymphoma cells transformed with recombinant mouse Fas

Quantity

0.1 mg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • Fas antigen, CD95, is a 45kDa cell-surface protein which can mediate apoptosis
  • It belongs to the TNF (tumor necrosis factor)/NGF receptor family
  • Expression of Fas has been described in the thymus, liver, heart, lung and ovary
  • Fas plays an important role in the apoptotic process that takes place during development
  • Monoclonal antibodies recognizing Fas such as Jo2 have cytolytic activity on cells expressing Fas
  • The cell death stimulated by Fas antibodies is characteristic of apoptosis and suggests that the lethal effects are a result of interaction of antibody with a functional Fas antigen as opposed to complement-mediated lysis
  • The Jo2 antibody recognizes mouse Fas
  • The Jo2 antibody shows cytolytic activity against cell lines expressing mouse Fas by inducing apoptosis
  • Intraperitoneal injections of Jo2 mAb have been shown to kill mice and induce apoptotic hepatocyte death
  • Jo2 mAb has been reported to immunoprecipitate mouse Fas as a 45kDa band from W4 cells
  • W4 cells are WR19L mouse lymphoma cells transformed with mouse Fas
  • The difference between the observed MW of Fas and that deduced from its amino acid sequence (Mr 34,971) may be due to glycosylation
  • Host Species: Hamster Clone: Jo2 Isotype: IgG2, λ 2 Species Reactivity: Mouse Immunogen: WR19L mouse lymphoma cells transformed with recombinant mouse Fas Flow Cytometry

Compare Similar Items

Show Difference

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BD Biosciences

BDB562499

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Antigen:
CD95

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Apo-1; Apt1; Fas; FASLG receptor; lpr; TNFR6; Tnfrsf6; TNR6

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2

Applications:
Flow Cytometry

Clone:
Jo2

Conjugate:
PE-CF594

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
WR19L mouse lymphoma cells transformed with recombinant mouse Fas

Quantity:
0.1 mg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

BDB562501

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Antigen:
Stat5 (pY694)

Classification:
Monoclonal

Concentration:
__

Description:
Signal transducer and activator of transcription 5; MGF; MPF

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
47/Stat5(pY694)

Conjugate:
PE-CF594

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated Sheep Stat5 Peptide

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB562504

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Antigen:
CD80

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Cd80; B7; B7-1; Cd28l; Ly-53; MIC17; TSA1

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2 κ

Applications:
Flow Cytometry

Clone:
16-10A1

Conjugate:
PE-CF594

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Mouse CD80 (B7) Transfected Cell Line

Quantity:
0.1 mg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB562505

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Antigen:
β-Catenin

Classification:
Monoclonal

Concentration:
__

Description:
CTNNB1; CTNB1; Catenin beta-1; catenin (cadherin-associated protein) beta 1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG1

Applications:
In vitro Assay, Immunofluorescence

Clone:
14/Beta-Catenin

Conjugate:
Alexa Fluor 488

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Mouse β-Catenin aa. 571-781

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.