BDB562505
β-Catenin Mouse, Alexa Fluor 488, Clone: 14/Beta-Catenin, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562505-Each-of-1 | In Stock | ₹ 44,362.86 |
BDB562505 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,362.86
GST (18%): ₹ 7,985.315
Total Price: ₹ 52,348.175
Antigen
β-Catenin
Classification
Monoclonal
Conjugate
Alexa Fluor 488
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen
Mouse β-Catenin aa. 571-781
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
In vitro Assay, Immunofluorescence
Clone
14/Beta-Catenin
Description
CTNNB1; CTNB1; Catenin beta-1; catenin (cadherin-associated protein) beta 1
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human, Mouse
Isotype
IgG1
Related Products
Description
- The 14/Beta-Catenin monoclonal antibody specifically binds to Beta-Catenin ( β -Catenin)
- β -Catenin is a 92 kDa protein that binds to the cytoplasmic tail of E-Cadherin
- The cadherins, transmembrane adhesion molecules, are found with catenins at adherens junctions (zonula adherens)
- Deletions in the cytoplasmic domain of E-Cadherin which eliminate catenin binding also result in a loss of cell adhesion, indicating that this binding is essential for E-Cadherin function
- Although the α - and β -Catenins have been cloned, very little is known about their biochemical roles
- However a link between β -Catenin and colon cancer has been described
- β -Catenin was found to co-immunoprecipitate with the APC tumor suppressor protein in human colorectal tumor cell lines, as well as in human kidney 293 cells
- E-Cadherin, however, was not detectable in these complexes
- Thus the APC-Catenin complex may be affecting the transmission of contact inhibition signals and/or the regulation of cell adhesion.
Compare Similar Items
Show Difference
Antigen: β-Catenin
Classification: Monoclonal
Conjugate: Alexa Fluor 488
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Mouse β-Catenin aa. 571-781
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: In vitro Assay, Immunofluorescence
Clone: 14/Beta-Catenin
Description: CTNNB1; CTNB1; Catenin beta-1; catenin (cadherin-associated protein) beta 1
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Isotype: IgG1
Antigen:
β-Catenin
Classification:
Monoclonal
Conjugate:
Alexa Fluor 488
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Mouse β-Catenin aa. 571-781
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
In vitro Assay, Immunofluorescence
Clone:
14/Beta-Catenin
Description:
CTNNB1; CTNB1; Catenin beta-1; catenin (cadherin-associated protein) beta 1
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Isotype:
IgG1
Antigen: B7-H4
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Recombinant human B7-H4 protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Flow Cytometry
Clone: MIH43
Description: VTCN1; VCTN1; B7 family member, H4; B7H4; B7h.5; B7S1; B7X
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
B7-H4
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Recombinant human B7-H4 protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Flow Cytometry
Clone:
MIH43
Description:
VTCN1; VCTN1; B7 family member, H4; B7H4; B7h.5; B7S1; B7X
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Smad1/Smad8
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated human Smad1 aa 456-465 peptide
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: N6-1233
Description: Smad1,Smad8/Smad9; MADH1, MADH9
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Isotype: IgG2a κ
Antigen:
Smad1/Smad8
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated human Smad1 aa 456-465 peptide
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
N6-1233
Description:
Smad1,Smad8/Smad9; MADH1, MADH9
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Isotype:
IgG2a κ
Antigen: CD27
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human T-CLL cells
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: M-T271
Description: TNFRSF7; TNF receptor superfamily, member 7; T14; Tp55; S152
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD27
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human T-CLL cells
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
M-T271
Description:
TNFRSF7; TNF receptor superfamily, member 7; T14; Tp55; S152
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ