BDB562506

B7-H4 Mouse anti-Human, Unlabeled, Clone: MIH43, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562506-Each-of-1 In Stock ₹ 17,882.04

BDB562506 - Each of 1

₹ 17,882.04

In Stock

Quantity

1

Base Price: ₹ 17,882.04

GST (18%): ₹ 3,218.767

Total Price: ₹ 21,100.807

Antigen

B7-H4

Classification

Monoclonal

Concentration

0.5mg/mL

Description

VTCN1; VCTN1; B7 family member, H4; B7H4; B7h.5; B7S1; B7X

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

MIH43

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Recombinant human B7-H4 protein

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • The MIH43 monoclonal antibody specifically binds to human B7-H4 (B7 family member, H4) that is encoded by the VTCN1 (V-set domain containing T cell activation inhibitor 1) gene
  • B7-H4 is a type I membrane glycoprotein with a calculated molecular weight of 30.89 kDa
  • It is also known as VCTN1, B7h.5, B7S1 (B7 superfamily member 1) or B7X
  • B7-H4 is a newly discovered member of the B7 family of costimulatory proteins
  • B7-H4 is not constitutively expressed on peripheral tissues
  • Its expression can be induced on macrophages, dendritic cells, B cells and T cells
  • By binding to its putative receptor, the function of B7-H4 was initially reported to be a negative regulator of T cell activation, proliferation and differentiation related to cytokine production and cytotoxic effector cell functions
  • B7-H4 is reportedly overexpressed in a variety tumors
  • B7-H4 expression by tumor macrophages appears to play a role in suppression antigen-specific T cell mediated immunity
  • Recent studies indicate that B7-H4 can also be a positive regulator of T cell responses
  • B7-H4 can be involved innate immunity as well, eg, by inhibiting neutrophil expansion.

Compare Similar Items

Show Difference

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BD Biosciences

BDB562506

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Antigen:
B7-H4

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
VTCN1; VCTN1; B7 family member, H4; B7H4; B7h.5; B7S1; B7X

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
MIH43

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Recombinant human B7-H4 protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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BD Biosciences

BDB562509

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Antigen:
Smad1/Smad8

Classification:
Monoclonal

Concentration:
__

Description:
Smad1,Smad8/Smad9; MADH1, MADH9

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
N6-1233

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated human Smad1 aa 456-465 peptide

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD27

Classification:
Monoclonal

Concentration:
__

Description:
TNFRSF7; TNF receptor superfamily, member 7; T14; Tp55; S152

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
M-T271

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human T-CLL cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Fischer Scientific

BDB562514

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Antigen:
CD27

Classification:
Monoclonal

Concentration:
__

Description:
TNFRSF7; TNF receptor superfamily, member 7; T14; Tp55; S152

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
M-T271

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
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Quantity:
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Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.