BDB564813

RUNX3 Mouse, Unlabeled, Clone: R3-5G4, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB564813-Each-of-1 In Stock ₹ 29,774.88

BDB564813 - Each of 1

₹ 29,774.88

In Stock

Quantity

1

Base Price: ₹ 29,774.88

GST (18%): ₹ 5,359.478

Total Price: ₹ 35,134.358

Antigen

RUNX3

Classification

Monoclonal

Concentration

0.5mg/mL

Description

AML2; AML-2; CBFA3; PEBP2aC; PEBP2A3

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human, Mouse

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

R3-5G4

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human RUNX3 Recombinant Protein

Quantity

0.1 mg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • The R3-5G4 monoclonal antibody specifically binds to Runt-related transcription factor 3 (RUNX3) which is also known as Acute myeloid leukemia 2 protein (AML2), Core-binding factor subunit alpha-3 (CBFA3), and Polyomavirus enhancer-binding protein 2 alpha C subunit (PEBP2aC)
  • RUNX3 is a member of the RUNX transcription factor family which includes RUNX1-3
  • RUNX3 is a key regulator of gene expression related to the development and differentiation of cells within the nervous and immune systems
  • In the immune system, RUNX3 is particularly involved in the commitment of CD8+ T cells in the thymus
  • RUNX3 is highly expressed and essential for the cytotoxic functions of NK cells, peripheral CD8+T cells and CD4+ CD8αα intraepithelial lymphocytes in the gut
  • RUNX3 als o plays a role in the differentiation and effector functions of Th1 cells
  • RUNX3 is activated downstream of the TGF-β signaling pathway and can play a role in tumor suppression
  • Aberrant expression of RUNX3 has been associated with tumorigenesis including the development of gastric and other cancers.

Compare Similar Items

Show Difference

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BD Biosciences

BDB564813

--


Antigen:
RUNX3

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
AML2; AML-2; CBFA3; PEBP2aC; PEBP2A3

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
R3-5G4

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human RUNX3 Recombinant Protein

Quantity:
0.1 mg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Img

BD Biosciences

BDB564814

--


Antigen:
RUNX3

Classification:
Monoclonal

Concentration:
__

Description:
AML2; AML-2; CBFA3; PEBP2aC; PEBP2A3

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
R3-5G4

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human RUNX3 Recombinant Protein

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB564815

--


Antigen:
CD29

Classification:
Monoclonal

Concentration:
__

Description:
ITGB1; Integrin beta-1; Integrin β1; FNRB; GPIIA; ITB1; MDF2; MSK12; VLA-4β

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
MAR4.

Conjugate:
Brilliant Violet 786

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide

Immunogen:
Purified Human α5β1 Fibronectin Receptor

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB564820

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Antigen:
CD365

Classification:
Monoclonal

Concentration:
__

Description:
TIM1; TIM; TIMD1; TIMD-1; HAVCR1; HAVCR-1; HAVCR; KIM1; KIM-1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
1D12

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human TIM-1 Recombinant Protein

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.