BDB563642
CD253 Mouse anti-Human, APC, Clone: RIK-2, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563642-Each-of-1 | In Stock | ₹ 28,063.68 |
BDB563642 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,063.68
GST (18%): ₹ 5,051.462
Total Price: ₹ 33,115.142
Antigen
CD253
Classification
Monoclonal
Concentration
0.2mg/mL
Description
TNFSF10; TRAIL; APO-2L; TL2
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1
Applications
Flow Cytometry
Clone
RIK-2
Conjugate
APC
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Human TRAIL Transfected Cell Line
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The RIK-2 monoclonal antibody specifically binds to CD253 which is also known as TRAIL (TNF-Related Apoptosis-Inducing Ligand) and Apo2 ligand (APO-2L)
- CD253 is a member of the Tumor Necrosis Factor Superfamily and is encoded by the TNFSF10 gene
- CD253 is a type II membrane protein that may be expressed as a full-length, cell surface associated protein as well as in a soluble form
- Both surface and soluble forms of TRAIL rapidly induce apoptosis by a wide range of cell lines but not by normal cells
- TRAIL is expressed by activated T cells, NK cells, dendritic cells, monocytes and by a variety of non-lymphoid cells
- TRAIL can bind to and exert apoptosis through DR4 (TRAIL-R1) and DR5 (TRAIL-R2) receptors
- It can also bind to decoy receptors, including DcR1/TRID/TRAIL-R3 and DcR2/TRUNDD/TRAIL-R4, and possibly OPG/TNFRSF11B, which may serve to regulate TRAIL activity
- TRAIL has been shown to be involved in T cell-mediated cytotoxicity, however its mechanism of action remains to be fully elucidated
- The RIK-2 clone was selected based on its ability to block TRAIL-mediated cytotoxic activity.
Compare Similar Items
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Antigen: CD253
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: TNFSF10; TRAIL; APO-2L; TL2
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1
Applications: Flow Cytometry
Clone: RIK-2
Conjugate: APC
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human TRAIL Transfected Cell Line
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD253
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
TNFSF10; TRAIL; APO-2L; TL2
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
RIK-2
Conjugate:
APC
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human TRAIL Transfected Cell Line
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Blimp-1
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Prdm1; PR domain zinc finger protein 1; Blimp1; PRDI-BF1; ZNFPR1A1
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: 5E7.
Conjugate: Alexa Fluor 647
Formulation: __
Immunogen: Mouse Blimp-1 Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Blimp-1
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Prdm1; PR domain zinc finger protein 1; Blimp1; PRDI-BF1; ZNFPR1A1
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
5E7.
Conjugate:
Alexa Fluor 647
Formulation:
__
Immunogen:
Mouse Blimp-1 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD49d
Classification: Monoclonal
Concentration: __
Description: Integrin α4 chain; Integrin alpha 4; ITGA4; IA4; alpha 4 subunit of VLA-4
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Baboon, Bovine, Canine, Cynomolgus, Human, Rhesus Monkey
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 9F10
Conjugate: PerCP-Cyanine5.5
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: __
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD49d
Classification:
Monoclonal
Concentration:
__
Description:
Integrin α4 chain; Integrin alpha 4; ITGA4; IA4; alpha 4 subunit of VLA-4
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Baboon, Bovine, Canine, Cynomolgus, Human, Rhesus Monkey
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
9F10
Conjugate:
PerCP-Cyanine5.5
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
__
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD95
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Apo-1; Apt1; Fas; FASLG receptor; lpr; TNFR6; Tnfrsf6; TNR6
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2 λ2
Applications: Flow Cytometry
Clone: Jo2
Conjugate: Brilliant Violet 510
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: WR19L mouse lymphoma cells transformed with recombinant mouse Fas
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD95
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Apo-1; Apt1; Fas; FASLG receptor; lpr; TNFR6; Tnfrsf6; TNR6
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2 λ2
Applications:
Flow Cytometry
Clone:
Jo2
Conjugate:
Brilliant Violet 510
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
WR19L mouse lymphoma cells transformed with recombinant mouse Fas
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.