BDB564802

CD272 (BTLA) Mouse anti-Human, Brilliant Violet 421, Clone:  J168-540, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB564802-Each-of-1 In Stock ₹ 26,309.70

BDB564802 - Each of 1

₹ 26,309.70

In Stock

Quantity

1

Base Price: ₹ 26,309.70

GST (18%): ₹ 4,735.746

Total Price: ₹ 31,045.446

Antigen

CD272 (BTLA)

Classification

Monoclonal

Concentration

0.2mg/mL

Description

BTLA1; B- and T-lymphocyte-associated protein

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

J168-540

Conjugate

Brilliant Violet 421

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human BTLA Recombinant Protein

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The J168-540 monoclonal antibody specifically binds to human CD272, also known as BTLA (B and T lymphocyte attenuator), an inhibitory receptor expressed in bone marrow and thymus on developing B and T cells
  • In the periphery, BTLA is expressed by B cells, T cells, bone marrow-derived dendritic cells, and macrophages
  • After T cell activation, BTLA appears to be expressed at higher levels on Th1 cell populations than in Th2 cell populations
  • Upon binding the herpesvirus entry mediator (HVEM/LIGHT-R/CD270), CD272 undergoes tyrosine phosphorylation and inhibits T cell proliferation in a BTLA-dependent manner
  • CD272 has structural similarities to two other lymphocyte inhibitory receptors, CTLA-4 and PD-1 and is a member of the CD28-like family of coreceptors
  • Based on these observations, CD272 is considered to be a negative regulator of lymphocyte activation and/or function
  • The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter)
  • BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Compare Similar Items

Show Difference

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BD Biosciences

BDB564802

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Antigen:
CD272 (BTLA)

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
BTLA1; B- and T-lymphocyte-associated protein

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
J168-540

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human BTLA Recombinant Protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BD Biosciences

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Antigen:
HLA-DQ

Classification:
Monoclonal

Concentration:
__

Description:
MHC class II HLA-DQ; MHC HLA-DQ

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
Tu169

Conjugate:
Brilliant Violet 421

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide

Immunogen:
__

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
Aiolos

Classification:
Monoclonal

Concentration:
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Description:
AIOLOS; AIO; IKZF3; ZNFN1A3

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
S50-895

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Aiolos Recombinant Protein

Quantity:
50 Tests

Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
RUNX3

Classification:
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Concentration:
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Description:
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Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
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Conjugate:
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Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

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Primary or Secondary:
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Content And Storage:
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