BDB565035
CD172a/b Mouse anti-Human, Alexa Fluor 647, Clone: SE5A5, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565035-Each-of-1 | In Stock | ₹ 20,106.60 |
BDB565035 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 20,106.60
GST (18%): ₹ 3,619.188
Total Price: ₹ 23,725.788
Antigen
CD172a/b
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide
Immunogen
Human SIRP alpha extracellular domain Recombinant Protein
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
SE5A5
Description
SIRP alpha/beta1; SIRPα/SIRPβ1; Signal Regulatory Protein α/β1
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The SE5A5 monoclonal antibody specifically binds to a common epitope on CD172a/ SIRPα (90 kDa) and CD172b/ SIRPβ 1(50 kDa)
- These transmembrane glycoproteins are members of the Signal Regulatory Protein (SIRP) family that, in turn, belongs to the Immunoglobulin superfamily
- The SIRP family is comprised of two subgroups, SIRPα and SIRPβ that are distinguished by the presence (α) or absence (β) of a cytoplasmic domain containing two immunoreceptor tyrosine-based inhibition motifs (ITIM)
- CD172a/ SIRPα is expressed on CD34+ stem/progenitor cells, cardiomyocytes, monocytes, macrophages, granulocytes, dendritic cells, and in the central nervous system
- It binds to CD47 and is implicated in mediating inhibitory signals via the ITIM/SHP-2 association
- CD172b/ SIRPβ to cellular activation signaling
- CD172b is expressed on myeloid cells, including peripheral blood monocytes and granulocytes
- It is not expressed on CD34+ cells
- CD172a and CD172b have complementary role s in signal regulation and may work together in tuning certain cellular responses to stimuli.
Compare Similar Items
Show Difference
Antigen: CD172a/b
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide
Immunogen: Human SIRP alpha extracellular domain Recombinant Protein
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: SE5A5
Description: SIRP alpha/beta1; SIRPα/SIRPβ1; Signal Regulatory Protein α/β1
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD172a/b
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide
Immunogen:
Human SIRP alpha extracellular domain Recombinant Protein
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
SE5A5
Description:
SIRP alpha/beta1; SIRPα/SIRPβ1; Signal Regulatory Protein α/β1
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD62L
Classification: Monoclonal
Conjugate: Brilliant Blue 515 (BB515)
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide
Immunogen: Human Peripheral Blood T Lymphocytes
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: SK11
Description: L-selectin; LECAM-1; SELL; LNHR; LSEL; LAM-1; LEU8; PLNHR; TQ-1; MEL-14
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype: IgG2a κ
Antigen:
CD62L
Classification:
Monoclonal
Conjugate:
Brilliant Blue 515 (BB515)
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide
Immunogen:
Human Peripheral Blood T Lymphocytes
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
SK11
Description:
L-selectin; LECAM-1; SELL; LNHR; LSEL; LAM-1; LEU8; PLNHR; TQ-1; MEL-14
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype:
IgG2a κ
Antigen: CD62L
Classification: Monoclonal
Conjugate: Brilliant Violet 711
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human Peripheral Blood T Lymphocytes
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: SK11
Description: L-selectin; LECAM-1; SELL; LNHR; LSEL; LAM-1; LEU8; PLNHR; TQ-1; MEL-14
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype: IgG2a κ
Antigen:
CD62L
Classification:
Monoclonal
Conjugate:
Brilliant Violet 711
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human Peripheral Blood T Lymphocytes
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
SK11
Description:
L-selectin; LECAM-1; SELL; LNHR; LSEL; LAM-1; LEU8; PLNHR; TQ-1; MEL-14
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype:
IgG2a κ
Antigen: CD62L
Classification: Monoclonal
Conjugate: Brilliant Violet 711
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human Peripheral Blood T Lymphocytes
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: SK11
Description: L-selectin; LECAM-1; SELL; LNHR; LSEL; LAM-1; LEU8; PLNHR; TQ-1; MEL-14
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype: IgG2a κ
Antigen:
CD62L
Classification:
Monoclonal
Conjugate:
Brilliant Violet 711
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human Peripheral Blood T Lymphocytes
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
SK11
Description:
L-selectin; LECAM-1; SELL; LNHR; LSEL; LAM-1; LEU8; PLNHR; TQ-1; MEL-14
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype:
IgG2a κ