BDB566255
CD47 Mouse anti-Human, Brilliant Violet 421, Clone: B6H12, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB566255-Each-of-1 | In Stock | ₹ 18,395.40 |
BDB566255 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 18,395.40
GST (18%): ₹ 3,311.172
Total Price: ₹ 21,706.572
Antigen
CD47
Clone
B6H12
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Classification
Monoclonal
Conjugate
Brilliant Violet 421
Gene Alias
IAP, CDw149, gp42, MER6, Neurophilin, OA3, Rh-related antigen
Immunogen
Purified human placental RGD-binding proteins
Quantity
25 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The B6H12 monoclonal antibody specifically binds to CD47, a 42-52 kDa N-linked glycan protein
- CD47 antigen, also known as integrin-associated protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes
- It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines
- CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells
- The B6H12 antibody is capable of blocking phagocytosis of microparticles by peripheral blood granulocytes
- It has also been reported to induce proliferation of CD3-activated T cells The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
- With an Ex Max of 407nm and Em Max at 421nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter)
- BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates
- BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences
- Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates
- Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.
Compare Similar Items
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Antigen: CD47
Clone: B6H12
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Gene Alias: IAP, CDw149, gp42, MER6, Neurophilin, OA3, Rh-related antigen
Immunogen: Purified human placental RGD-binding proteins
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD47
Clone:
B6H12
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Gene Alias:
IAP, CDw149, gp42, MER6, Neurophilin, OA3, Rh-related antigen
Immunogen:
Purified human placental RGD-binding proteins
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD103
Clone: Ber-ACT8
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Gene Alias: ITGAE; Integrin alpha-E; ITAE; HML-1 antigen; Mucosal lymphocyte 1; HUMINAE
Immunogen: Human MAPS16 T Cell Line
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon™ BV421 under optimum conditions and unconjugated antibody and free BD Horizon™ BV421 were removed.
Antigen:
CD103
Clone:
Ber-ACT8
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Gene Alias:
ITGAE; Integrin alpha-E; ITAE; HML-1 antigen; Mucosal lymphocyte 1; HUMINAE
Immunogen:
Human MAPS16 T Cell Line
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon™ BV421 under optimum conditions and unconjugated antibody and free BD Horizon™ BV421 were removed.
Antigen: CD95
Clone: DX2
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Gene Alias: APO-1, FAS, TNFRSF6, APT1, ALPS1A, FAS1, FASTM, FASLG receptor
Immunogen: Human CD95-transfected L Cells
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD95
Clone:
DX2
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Gene Alias:
APO-1, FAS, TNFRSF6, APT1, ALPS1A, FAS1, FASTM, FASLG receptor
Immunogen:
Human CD95-transfected L Cells
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD107A
Clone: H4A3
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Gene Alias: LAMP1, LAMP-1, LAMPA, LGP120
Immunogen: Human Adult Adherent Peripheral Blood Cells
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD107A
Clone:
H4A3
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Gene Alias:
LAMP1, LAMP-1, LAMPA, LGP120
Immunogen:
Human Adult Adherent Peripheral Blood Cells
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.