BDB566329
NKp80 Mouse anti-Human, PE, Clone: 5D12, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB566329-Each-of-1 | In Stock | ₹ 31,639.50 |
BDB566329 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,639.50
GST (18%): ₹ 5,695.11
Total Price: ₹ 37,334.61
Antigen
NKp80
Clone
5D12
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Classification
Monoclonal
Conjugate
PE
Gene Alias
KLRF1, CLEC5C, C-type lectin domain family 5 member C, ML
Immunogen
Human NKp80 extracellular domain
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- The 5D12 monoclonal antibody specifically binds to NKp80 which is also known as C-type lectin domain family 5 member C (CLEC5C)
- NKp80 is a single-pass type II transmembrane glycoprotein that contains a C-type lectin extracellular domain and is expressed as a ñ80 kDa disulfide-linked homodimer
- NKp80 is encoded by KLRF1 /(Killer cell lectin-like receptor subfamily F member 1) which maps to the NK-gene complex (NKC)
- NKp80 is expressed on most NK cells, and subsets ofγδ T cellsand effector-memory CD8αβT cells
- NKp80 is not present in rodents
- NKp80 is an activating coreceptor that induces NK cell-mediated cytotoxicity and proinflammatory cytokine (eg, IFN-γand TNF) production upon interaction with its ligand, AICL (Activation induced C type lectin)
- AICL is encoded by CLEC2B /that is selectively expressed on myeloid cells including activated monocytes, macrophages, and granulocytes
- NKp80 can reportedly transduce signals through an atypical hemi-ITAM-like sequence motif and Syk kinase to trigger cellular responses
- R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae
- It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule
- This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.
Compare Similar Items
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Antigen: NKp80
Clone: 5D12
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Classification: Monoclonal
Conjugate: PE
Gene Alias: KLRF1, CLEC5C, C-type lectin domain family 5 member C, ML
Immunogen: Human NKp80 extracellular domain
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
NKp80
Clone:
5D12
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Classification:
Monoclonal
Conjugate:
PE
Gene Alias:
KLRF1, CLEC5C, C-type lectin domain family 5 member C, ML
Immunogen:
Human NKp80 extracellular domain
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD158f
Clone: UP-R1
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1
Classification: Monoclonal
Conjugate: Brilliant Violet 421
Gene Alias: CD158F, CD158F1, CD158F2, KI2LA, KIR2DL5, KIR2DL5A, KIR2DL5B
Immunogen: Human CD158f Recombinant Protein
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD158f
Clone:
UP-R1
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1
Classification:
Monoclonal
Conjugate:
Brilliant Violet 421
Gene Alias:
CD158F, CD158F1, CD158F2, KI2LA, KIR2DL5, KIR2DL5A, KIR2DL5B
Immunogen:
Human CD158f Recombinant Protein
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: __
Clone: __
Formulation: __
Host Species: __
Purification Method: __
Regulatory Status: __
Target Species: __
Isotype: __
Classification: __
Conjugate: __
Gene Alias: __
Immunogen: __
Quantity: 200 μg
Primary or Secondary: __
Content And Storage: __
Antigen:
__
Clone:
__
Formulation:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Target Species:
__
Isotype:
__
Classification:
__
Conjugate:
__
Gene Alias:
__
Immunogen:
__
Quantity:
200 μg
Primary or Secondary:
__
Content And Storage:
__
Antigen: CD3
Clone: MEM-57
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Gene Alias: CD3-epsilon, CD3E, T-cell surface antigen T3/Leu-4 epsilon chain, T3E, TCRE
Immunogen: Human Thymocytes and T Lymphocytes
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD3
Clone:
MEM-57
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Gene Alias:
CD3-epsilon, CD3E, T-cell surface antigen T3/Leu-4 epsilon chain, T3E, TCRE
Immunogen:
Human Thymocytes and T Lymphocytes
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.