BDB569265

IFN-γ Mouse anti-Human, RB545, Clone: B27, BD Horizon™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB569265-Each-of-1 In Stock ₹ 35,764.08

BDB569265 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

IFN-γ

Classification

Monoclonal

Conjugate

RB545

Gene Alias

IFNG; Interferon-gamma; Interferon-γ; Type II interferon; MAF

Immunogen

Human IFN-γ Recombinant Protein

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Excitation/Emission

Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications

Flow Cytometry

Clone

B27

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Gene ID (Entrez)

15978,16176,25712,3458,380793,4049

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype

IgG1 κ

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Description

  • The B27 monoclonal antibody specifically binds to human interferon-γ (IFN-γ), a 14-18 kDa glycoprotein containing 143 amino acid residues
  • IFN-γ is a potent multifunctional cytokine produced by several activated cell types including NK, NKT, CD4+TCRαβ+, CD8+TCRαβ+, and TCRγδ+ T cells
  • IFN-γ exerts its biological effects through specific binding to the high-affinity IFN-γ receptor complex comprised of IFN-γRα (CD119) and IFN-γRβ subunits
  • In addition to its antiviral effects, IFN-γ upregulates a number of lymphoid cell functions including the antimicrobial and anti-tumor responses of macrophages, NK cells, and neutrophils
  • In addition, IFN-γ influences the regulation of proliferation, differentiation, and effector responses of B cell and T cell subsets
  • These influences can involve IFN-γ's capacity to boost MHC class I and II expression by antigen-presenting cells as well as direct effects on B cells and T cells themselves
  • B27 is a neutralizing antibody
  • The use of B27 antibody for epitope mapping of human IFN-γ has been described
  • The B27 antibody has been reported not to bind to denatured IFN-γ
  • IFN-γ Monoclonal antibody specifically detects IFN-γ in Human samples
  • It is validated for Intracellular Staining (Flow Cytometry)

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB569265

--


Antigen:
IFN-γ

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
IFNG; Interferon-gamma; Interferon-γ; Type II interferon; MAF

Immunogen:
Human IFN-γ Recombinant Protein

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
B27

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
15978,16176,25712,3458,380793,4049

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG1 κ

Img

BD Biosciences

BDB569267

--


Antigen:
CD25 (IL-2 Receptor α)

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55

Immunogen:
Human Phytohemagglutinin-activated T Cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
2A3

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
3559

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG1 κ

Img

BD Biosciences

BDB569268

--


Antigen:
CD25 (IL-2 Receptor α)

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55

Immunogen:
Human Phytohemagglutinin-activated T Cells

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
2A3

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
3559

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG1 κ

Img

BD Biosciences

BDB569269

--


Antigen:
CD123 (IL-3 Receptor α)

Classification:
Monoclonal

Conjugate:
RB545

Gene Alias:
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha

Immunogen:
Human IL-3Ra-transfected cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Excitation/Emission:
Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm

Applications:
Flow Cytometry

Clone:
7G3

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Gene ID (Entrez):
3563

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.

Isotype:
IgG2a κ