BDB610442

c-Cbl Mouse, Unlabeled, Clone: 17, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB610442-Each-of-1 In Stock ₹ 48,640.86

BDB610442 - Each of 1

₹ 48,640.86

In Stock

Quantity

1

Base Price: ₹ 48,640.86

GST (18%): ₹ 8,755.355

Total Price: ₹ 57,396.215

Antigen

c-Cbl

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Quantity

150 μg

Research Discipline

Cell Biology

Target Species

Canine, Chicken, Human, Mouse, Rat

Isotype

IgG1

Applications

Western Blot

Clone

17

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • cbl was identified in the genome of a transforming retrovirus from a mouse pre-B cell lymphoma
  • The product of mammalian c-cbl, p120[cbl], is a widely expressed cytoplasmic protein with several distinctive domains including a RING finger motif and a large proline-rich domain
  • Although the normal cellular function of c-Cbl has not yet been determined, it associates with many well known signal transduction proteins
  • In lymphoid cells, c-Cbl is a substrate of TCR-activated protein tyrosine kinases
  • In addition, stimulation with EGF, PDGF, FGF, or NGF results in tyrosine-phosphorylation of c-Cbl in lymphoid and other cell types
  • It forms a signaling complex with Grb2 in T cells and is a SH3 and SH2 binding protein which associates with many other cytoplasmic signaling proteins including Btk, Src, fyn, lck, and the β isoform of PI-3 kinase
  • Thus, c-Cbl may be an important adaptor protein in growth factor and T-cell receptor signaling pathways
  • Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Compare Similar Items

Show Difference

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Fischer Scientific

BDB610442

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Antigen:
c-Cbl

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
17

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

BDB610445

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Antigen:
Casein Kinase Iε

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human Casein Kinase Iε aa. 248-414

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
1

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

BDB610446

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Antigen:
Casein Kinase Iε

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human Casein Kinase Iε aa. 248-414

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
1

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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BDB610451

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Antigen:
B2 Bradykinin Receptor

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Human, Rat

Isotype:
IgG2b κ

Applications:
Western Blot

Clone:
20

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.