BDB611226

Glucocorticoid Receptor Mouse anti-Human, Unlabeled, Clone: 41, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB611226-Each-of-1 In Stock ₹ 24,470.16

BDB611226 - Each of 1

₹ 24,470.16

In Stock

Quantity

1

Base Price: ₹ 24,470.16

GST (18%): ₹ 4,404.629

Total Price: ₹ 28,874.789

Antigen

Glucocorticoid Receptor

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Human Glucocorticoid Receptor α aa. 176-289

Quantity

50 μg

Research Discipline

Cell Biology

Target Species

Human

Isotype

IgG1

Applications

Western Blot

Clone

41

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Steroid hormone receptors are hormone activated transcriptional regulators that influence genes required for embryonic development and adult homeostasis
  • One member of the steroid hormone family is the glucocorticoid receptor
  • It contains AF1 and AF2 transactivation domains, a DNA binding domain, and ligand binding domain
  • Ligand bound glucocorticoid receptors dimerize at specific palindromic sequences called glucocorticoid response elements (GREs) in the cis-regulatory region of target genes
  • Both AF1 and AF2 may be important for initiation or regulation of transcription by interacting with components of the initiation complex or other intermediary factors
  • In addition to transactivation, glucocorticoid receptors may also regulate transcription through transrepression of target genes
  • Although mechanisms of transrepression are not completely understood; DNA binding alone, DNA binding plus interaction with other transcription factors, or protein-protein interaction without DNA binding are mechanisms that have been implicated
  • Thus, glucocorticoid receptors function in the regulation of specific genes that are essential for human development and homeostasis
  • Host Species: Mouse Clone: 41 Isotype: IgG1 Species Reactivity: Human Immunogen: Human Glucocorticoid Receptor α aa
  • 176-289 Formula Weight [Chemical]: 94kDa Immunofluorescence, Western Blotting

Compare Similar Items

Show Difference

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Fischer Scientific

BDB611226

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Antigen:
Glucocorticoid Receptor

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human Glucocorticoid Receptor α aa. 176-289

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgG1

Applications:
Western Blot

Clone:
41

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
Glucocorticoid Receptor

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human Glucocorticoid Receptor α aa. 176-289

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgG1

Applications:
Western Blot

Clone:
41

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
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Concentration:
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Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
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Quantity:
50 μg

Research Discipline:
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Target Species:
Human

Isotype:
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Applications:
Western Blot

Clone:
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Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
p70 [S6K]

Classification:
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Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
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Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
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Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.