BDB612243

PKA (RIIα) Mouse, Unlabeled, Clone: 40, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB612243-Each-of-1 In Stock ₹ 47,571.36

BDB612243 - Each of 1

₹ 47,571.36

In Stock

Quantity

1

Base Price: ₹ 47,571.36

GST (18%): ₹ 8,562.845

Total Price: ₹ 56,134.205

Antigen

PKA (RIIα)

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Human PKA[RIIα] aa. 1-404

Quantity

150 μg

Research Discipline

Cell Biology

Target Species

Canine, Human, Mouse, Rat

Isotype

IgG1

Applications

Western Blot

Clone

40

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • cAMP-dependent Protein Kinase (PKA) is composed of two distinct subunits: catalytic(C) and regulatory (R)
  • Four regulatory subunits have been identified: RIα, RIβ, RIIα, and RIIβ.These subunits define type I and II cAMP-dependent protein kinases
  • Following binding of cAMP, the regulatory subunits dissociate from the catalytic subunits, rendering the enzyme active
  • Type I and type II holoenzymes have three potential C subunits (Cα, Cβ, or Cγ)
  • Type II PKA can be distinguished by autophosphorylation of the R-subunits, while type I PKA binds Mg/ATP with high affinity
  • Most cells express both type I and type II PKAs
  • Although the Rα isoforms are ubiquitously expressed, the Rβ isoforms are predominant in nervous and adipose tissues
  • Expression of the RIα subunit is modulated during muscle and adipocyte differentiation in vitro
  • Immunofluorescence, Immunoprecipitation, Western Blotting

Compare Similar Items

Show Difference

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Fischer Scientific

BDB612243

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Antigen:
PKA (RIIα)

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human PKA[RIIα] aa. 1-404

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
40

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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BDB612260

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Antigen:
p115

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Rat p115 aa. 843-955

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
15

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
ICBP90

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human ICBP90 aa. 199-298

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgG2a

Applications:
Western Blot

Clone:
28

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
MAD2B/Rev7

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human MAD2B aa. 81-180

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Human

Isotype:
IgG1

Applications:
Western Blot

Clone:
14

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.