BDB612701
Stat6 (pY641) Mouse anti-Human, PE, Clone: 18/P-STAT6, BD
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB612701-Each-of-1 | In Stock | ₹ 27,165.30 |
BDB612701 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,165.30
GST (18%): ₹ 4,889.754
Total Price: ₹ 32,055.054
Antigen
Stat6 (pY641)
Classification
Monoclonal
Conjugate
PE
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Phosphorylated Human Stat6 (pY641)
Quantity
50 Tests
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG2a
Applications
Flow Cytometry
Clone
18/P-STAT6
Description
Signal transducer and activator of transcription 6; IL-4 Stat
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- Interleukin-4 (IL-4), a major immunoregulatory cytokine, is secreted by activated T lymphocytes, basophils, and mast cells and plays an important role in modulating T helper cell lineage development
- It induces specific gene expression via the tyrosine phosphorylation of Stat6 at tyrosine 641 (Y641)
- Stat6, a member of the s ignal t ransducers and a ctivators of transcription protein family, mediates signals for IL-4 and, possibly, IL-13
- While Stat6 is widely expressed in human tissues, it exhibits elevated expression in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung, and placenta
- Following cytokine receptor ligation, Jak kinases are activated and phosphorylate the cytoplasmic tails of the oligomerized receptors
- The SH3:SH2 domain of Stat6 associates with tyrosine-phosphorylated IL-4 receptor and the proximal Jak kinase phosphorylates Stat6 at Y641 on the C-terminal side of the SH2 domain
- Stat6 is then released from the receptor, dimerizes, and is thought to contact the basal transcription machinery by binding to p300/CBP
- Thus, Stat6 mediates the IL-4 signal and is essential for the proper development of adaptive immunity.
Compare Similar Items
Show Difference
Antigen: Stat6 (pY641)
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Stat6 (pY641)
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG2a
Applications: Flow Cytometry
Clone: 18/P-STAT6
Description: Signal transducer and activator of transcription 6; IL-4 Stat
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Stat6 (pY641)
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Stat6 (pY641)
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG2a
Applications:
Flow Cytometry
Clone:
18/P-STAT6
Description:
Signal transducer and activator of transcription 6; IL-4 Stat
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Gαq
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human Gαq aa. 22-31
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Chicken, Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 10
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Gαq
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human Gαq aa. 22-31
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Chicken, Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
10
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: eNOS (pT495), Phospho-Specific
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human Phosphorylated eNOS Peptide
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 31
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
eNOS (pT495), Phospho-Specific
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human Phosphorylated eNOS Peptide
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
31
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: PKCθ (pT538)
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human PKCθ Peptide
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG2a
Applications: Western Blot
Clone: 19
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
PKCθ (pT538)
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human PKCθ Peptide
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG2a
Applications:
Western Blot
Clone:
19
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.