BDB740181
CD195 Mouse anti-Human, Brilliant Violet 510, Clone: 2D7/CCR5, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB740181-Each-of-1 | In Stock | ₹ 47,614.14 |
BDB740181 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
CD195
Classification
Monoclonal
Concentration
0.2mg/mL
Description
CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
2D7/CCR5
Conjugate
Brilliant Violet 510
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Human CCR5 Transfected Cell Line
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The 2D7/CCR5 monoclonal antibody specifically binds to the human chemokine receptor CCR5, also known as CD195
- CCR5 is a seven transmembrane-spanning G protein-associated molecule that belongs to the beta chemokine receptor family and expressed on a subset of T lymphocytes (CD3+CD45RO+CD95+)
- CCR5 regulates lymphocyte chemotaxis activation and transendothelial migration during inflammation by signaling a response to at least three chemokines: Regulated upon Activation Normal T-cell Expressed and Secreted (RANTES), Macrophage Inflammatory Protein-1 (MIP-1), and Monocyte Chemoattractant Protein 2 (MCP-2)
- Additionally, CCR5 has been found to be a coreceptor for macrophage-tropic HIV-1 on CD4+ cells, a characteristic that is important in viral transmission
- Reports indicate that individuals who have partial (heterozygous) or complete (homozygous) deletion of the CCR5 allele demonstrate resistance to HIV infection
- This antibody has been shown to block ligand and gp120 binding
- It is also able to neutralize HIV infection
- The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes
- With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50-nm) filter set
- BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser.
Compare Similar Items
Show Difference
Antigen: CD195
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: 2D7/CCR5
Conjugate: Brilliant Violet 510
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human CCR5 Transfected Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD195
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
2D7/CCR5
Conjugate:
Brilliant Violet 510
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human CCR5 Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD63
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: LAMP-3; ME491; MLA-1; Granulophysin; Ptgr40; NGA; gp55
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: H5C6
Conjugate: Brilliant Violet 510
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human Splenic Adherent Cells
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD63
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
LAMP-3; ME491; MLA-1; Granulophysin; Ptgr40; NGA; gp55
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
H5C6
Conjugate:
Brilliant Violet 510
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human Splenic Adherent Cells
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD183
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: CXCR3; C-X-C chemokine receptor type 3; GPR9; IP10R; MigR; CKRL2; CMKAR3
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 1C6/CXCR3
Conjugate: Brilliant Violet 510
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human CXCR3 Peptide
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD183
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
CXCR3; C-X-C chemokine receptor type 3; GPR9; IP10R; MigR; CKRL2; CMKAR3
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
1C6/CXCR3
Conjugate:
Brilliant Violet 510
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human CXCR3 Peptide
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: HLA-A2
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: HLA class I histocompatibility antigen A2 alpha chain; HLA-A2
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: BB7.2
Conjugate: Brilliant Violet 510
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: __
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
HLA-A2
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
HLA class I histocompatibility antigen A2 alpha chain; HLA-A2
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
BB7.2
Conjugate:
Brilliant Violet 510
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.