BDB740319

CD294 (CRTH2) Rat anti-Human, BUV395, Clone: BM16, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740319-Each-of-1 In Stock ₹ 47,400.24

BDB740319 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

CD294 (CRTH2)

Classification

Monoclonal

Concentration

0.2mg/mL

Description

CRTH2; PTGDR2 ; Prostaglandin D2 receptor 2; DL1R; DP2; GPR44

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

BM16

Conjugate

Brilliant Ultraviolet 395

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human CRTH2 Transfected Cell Line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The BM16 monoclonal antibody specifically binds to CD294
  • CD294 is encoded by PTGDR2 (Prostaglandin D2 receptor 2) and is also known as CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells), GPR44 (G protein-coupled receptor 44), DL1R, and DP2
  • CD294 is a member of the G protein-coupled leukocyte chemoattractant receptor family
  • CD294 is expressed on Th2 cells and type-2 innate lymphoid cells (ILC2), but not Th1 type cells
  • CD294 is detectable on CD4+ T cells in fresh PBMC but not on B cells and NK cells
  • CD294 is also expressed on peripheral blood basophils and eosinophils, suggesting its involvement allergic reactions
  • Phenotypic analysis of CD4+ T cells expressing CRTH2 demonstrated that they were also CD45RA-negative and CD45RO+ and CD25+
  • These cells produce Th2- but little or no Th1-type cytokines upon stimulation with PMA and Ionomycin
  • The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
  • This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
  • With an Ex Max at 348nm and an Em Max at 395nm, BD Horizon BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.

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Show Difference

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BD Biosciences

BDB740319

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Antigen:
CD294 (CRTH2)

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
CRTH2; PTGDR2 ; Prostaglandin D2 receptor 2; DL1R; DP2; GPR44

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
BM16

Conjugate:
Brilliant Ultraviolet 395

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human CRTH2 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB740320

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Antigen:
CD274

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
B7-H1, PD-L1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
MIH1

Conjugate:
Brilliant Ultraviolet 395

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
__

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
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Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
RL73 (also known as RL73.2)

Conjugate:
Brilliant Ultraviolet 395

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse EL4 Cell Subline

Quantity:
50 μg

Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD357 (GITR)

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
GITR; Gitr; glucocorticoid-induced TNFR-related protein; Tnfrsf18; AITR

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2b

Applications:
Flow Cytometry

Clone:
DTA-1

Conjugate:
Brilliant Ultraviolet 395

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse CD25+ CD4+ T Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.