BDB742638
CD11b Mouse anti-Human, Brilliant Violet 510, Clone: D12, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB742638-Each-of-1 | In Stock | ₹ 47,400.24 |
BDB742638 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,400.24
GST (18%): ₹ 8,532.043
Total Price: ₹ 55,932.283
Antigen
CD11b
Clone
D12
Conjugate
Brilliant Violet 510
Gene Alias
MAC-1A, Mac-1, ITGAM, Integrin alpha M, CR3A, CR-3 alpha, Mo1, SLEB6
Immunogen
Human peripheral blood T lymphocytes
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Description
- The D12 monoclonal antibody specifically binds to CD11b which is also known as Integrin alpha M (IntegrinαM), Mac-1 subunit alpha (Mac-1a) or complement receptor 3 alpha chain (CR3a)
- CD11b is encoded by ITGAM /(integrin subunit alpha M) and belongs to the integrin alpha subunit gene family
- CD11b is expressed as a ñ165-kDa type I transmembrane glycoprotein that associates with the ñ95-kDa integrin β2(CD18) to form the heterodimeric CD11b/CD18 (αM/β2) complex which also known as Mac-1 or CR3
- CD11b is expressed on monocytes, dendritic cells, granulocytes, as well as on some T cells, B cells, and NK cells
- CD11b functions in cell-cell and cell-substrate interactions and is a receptor for multiple ligands including inactivated C3b (iC3b), ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50) or fibrinogen
- Mac-1 regulates leucocyte adhesion and migration, as well as phagocytosis of opsonized particles
- The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes
- With an Ex Max of 405nm and Em Max at 510nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50nm) filter set
- BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser
- BV510 is a polymer-based dye that is brighter than BD Horizon V500
- Due to similar excitation and emission properties, BD Horizon BV510 and BD Horizon V500 cannot be used simultaneously.
Compare Similar Items
Show Difference
Antigen: CD11b
Clone: D12
Conjugate: Brilliant Violet 510
Gene Alias: MAC-1A, Mac-1, ITGAM, Integrin alpha M, CR3A, CR-3 alpha, Mo1, SLEB6
Immunogen: Human peripheral blood T lymphocytes
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD11b
Clone:
D12
Conjugate:
Brilliant Violet 510
Gene Alias:
MAC-1A, Mac-1, ITGAM, Integrin alpha M, CR3A, CR-3 alpha, Mo1, SLEB6
Immunogen:
Human peripheral blood T lymphocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD11b
Clone: D12
Conjugate: Brilliant Violet 605
Gene Alias: MAC-1A, Mac-1, ITGAM, Integrin alpha M, CR3A, CR-3 alpha, Mo1, SLEB6
Immunogen: Human peripheral blood T lymphocytes
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD11b
Clone:
D12
Conjugate:
Brilliant Violet 605
Gene Alias:
MAC-1A, Mac-1, ITGAM, Integrin alpha M, CR3A, CR-3 alpha, Mo1, SLEB6
Immunogen:
Human peripheral blood T lymphocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD11b
Clone: D12
Conjugate: Brilliant Violet 650
Gene Alias: MAC-1A, Mac-1, ITGAM, Integrin alpha M, CR3A, CR-3 alpha, Mo1, SLEB6
Immunogen: Human peripheral blood T lymphocytes
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD11b
Clone:
D12
Conjugate:
Brilliant Violet 650
Gene Alias:
MAC-1A, Mac-1, ITGAM, Integrin alpha M, CR3A, CR-3 alpha, Mo1, SLEB6
Immunogen:
Human peripheral blood T lymphocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD11b
Clone: D12
Conjugate: Brilliant Violet 711
Gene Alias: MAC-1A, Mac-1, ITGAM, Integrin alpha M, CR3A, CR-3 alpha, Mo1, SLEB6
Immunogen: Human peripheral blood T lymphocytes
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD11b
Clone:
D12
Conjugate:
Brilliant Violet 711
Gene Alias:
MAC-1A, Mac-1, ITGAM, Integrin alpha M, CR3A, CR-3 alpha, Mo1, SLEB6
Immunogen:
Human peripheral blood T lymphocytes
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ