BDB742829
CD277 Mouse anti-Human, Brilliant Violet 650, Clone: 232-5, BD Optibuild™
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB742829-Each-of-1 | In Stock | ₹ 47,400.24 |
BDB742829 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,400.24
GST (18%): ₹ 8,532.043
Total Price: ₹ 55,932.283
Antigen
CD277
Clone
232-5
Conjugate
Brilliant Violet 650
Gene Alias
CD277, Butyrophilin 3, BTN3, BTN3A1, BTN3A2, BTN3A3, BTN3.1, BTN3.2, BTN3.3
Immunogen
Human BTN3A3
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Description
- The 232-5 monoclonal antibody specifically recognizes Butyrophilin 3 (BTN3), which is also known as CD277
- BTN3 is comprised of three structurally related members, BTN3A1, BTN3A2, and BTN3A3
- BTN3 molecules are transmembrane type 1 glycoproteins that belong to the Ig superfamily
- The 232-5 antibody recognizes the variable region of the extracellular domains of BTN3 molecules
- BTN3 molecules are differentially expressed by T, NKT, B, and NK cells, monocytes, macrophages, dendritic cells, as well as some stem cells and tumor cells
- BTN3 expression is decreased upon lymphocyte activation
- The extracellular domain of CD277 is structurally related to the B7 family of proteins that regulate T cell activation
- A soluble form of the 232-5 antibody can serve as an agonist in BTN3-mediated regulation of anti-CD3±anti-CD28 antibody activated CD4+ or CD8+ T cells
- The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
- BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- However, the spillover can be corrected through compensation as with any other dye combination
- BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- BV650 will have moderate spillover into the BD Horizon™ BV711 detector.
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Antigen: CD277
Clone: 232-5
Conjugate: Brilliant Violet 650
Gene Alias: CD277, Butyrophilin 3, BTN3, BTN3A1, BTN3A2, BTN3A3, BTN3.1, BTN3.2, BTN3.3
Immunogen: Human BTN3A3
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD277
Clone:
232-5
Conjugate:
Brilliant Violet 650
Gene Alias:
CD277, Butyrophilin 3, BTN3, BTN3A1, BTN3A2, BTN3A3, BTN3.1, BTN3.2, BTN3.3
Immunogen:
Human BTN3A3
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD277
Clone: 232-5
Conjugate: Brilliant Violet 711
Gene Alias: CD277, Butyrophilin 3, BTN3, BTN3A1, BTN3A2, BTN3A3, BTN3.1, BTN3.2, BTN3.3
Immunogen: Human BTN3A3
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD277
Clone:
232-5
Conjugate:
Brilliant Violet 711
Gene Alias:
CD277, Butyrophilin 3, BTN3, BTN3A1, BTN3A2, BTN3A3, BTN3.1, BTN3.2, BTN3.3
Immunogen:
Human BTN3A3
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD277
Clone: 232-5
Conjugate: Brilliant Violet 786
Gene Alias: CD277, Butyrophilin 3, BTN3, BTN3A1, BTN3A2, BTN3A3, BTN3.1, BTN3.2, BTN3.3
Immunogen: Human BTN3A3
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD277
Clone:
232-5
Conjugate:
Brilliant Violet 786
Gene Alias:
CD277, Butyrophilin 3, BTN3, BTN3A1, BTN3A2, BTN3A3, BTN3.1, BTN3.2, BTN3.3
Immunogen:
Human BTN3A3
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD277
Clone: 232-5
Conjugate: Brilliant Ultraviolet 395
Gene Alias: CD277, Butyrophilin 3, BTN3, BTN3A1, BTN3A2, BTN3A3, BTN3.1, BTN3.2, BTN3.3
Immunogen: Human BTN3A3
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD277
Clone:
232-5
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
CD277, Butyrophilin 3, BTN3, BTN3A1, BTN3A2, BTN3A3, BTN3.1, BTN3.2, BTN3.3
Immunogen:
Human BTN3A3
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ