BDB742982

CD158e1 (NKB1) Mouse anti-Human, Brilliant Violet 786, Clone: DX9, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB742982-Each-of-1 In Stock ₹ 47,400.24

BDB742982 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

CD158e1 (NKB1)

Clone

DX9

Conjugate

Brilliant Violet 786

Gene Alias

KIR3DL1, CD158E, CD158E1, KIR antigen 3DL1, KIR, KI3L1, NKAT-3, NKB1, NKB1B

Immunogen

Human NK Cell Clone

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Description

  • The DX9 monoclonal antibody specifically binds to CD158e1, also known as NKB1
  • CD158e1 functions as a killer cell inhibitory receptor (KIR) and is encoded by KIR3DL1 /(Killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail)
  • CD158e1 is a 70 kDa glycoprotein that belongs to the Ig superfamily
  • It is expressed on a subset of natural killer cells and a small subset of T cells
  • Expression of CD158e1 has been observed to vary among individuals
  • KIR molecules specifically recognize a certain group of HLA class I antigens
  • Interaction of CD158e1 with specific HLA-B antigen on a target cell appears to inhibit cell-mediated cytotoxicity by delivering a negative signal that prevents lymphocyte activation
  • It is suggested that this MHC class I-KIR interaction works as a signaling mechanism that regulates NK and T-cell responses to antigenic challenge
  • The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm
  • BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter)
  • BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm
  • BV786 offers a bright choice for the 6th detector off the violet laser.

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BD Biosciences

BDB742982

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Antigen:
CD158e1 (NKB1)

Clone:
DX9

Conjugate:
Brilliant Violet 786

Gene Alias:
KIR3DL1, CD158E, CD158E1, KIR antigen 3DL1, KIR, KI3L1, NKAT-3, NKB1, NKB1B

Immunogen:
Human NK Cell Clone

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB742983

--


Antigen:
CD158e1 (NKB1)

Clone:
DX9

Conjugate:
Brilliant Ultraviolet 395

Gene Alias:
KIR3DL1, CD158E, CD158E1, KIR antigen 3DL1, KIR, KI3L1, NKAT-3, NKB1, NKB1B

Immunogen:
Human NK Cell Clone

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

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BD Biosciences

BDB742991

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Antigen:
Siglec-1 (CD169)

Clone:
7-239

Conjugate:
Brilliant Violet 421

Gene Alias:
Sialoadhesin, SN, SIGLEC1, Siglec-1, Sialic acid-binding Ig-like lectin 1

Immunogen:
Human Rhinovirus-infected Dendritic Cells

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB742992

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Antigen:
Siglec-1 (CD169)

Clone:
7-239

Conjugate:
Brilliant Violet 510

Gene Alias:
Sialoadhesin, SN, SIGLEC1, Siglec-1, Sialic acid-binding Ig-like lectin 1

Immunogen:
Human Rhinovirus-infected Dendritic Cells

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ