CD87 Mouse anti-Human, Brilliant Violet 605, Clone: VIM5 (also known as VIM-5), BD Optibuild™

Description

• The VIM5 monoclonal antibody specifically recognizes CD87
• CD87 is also known as the urokinase plasminogen activator receptor (uPA-R)
• CD87 is a 50-65 kDa single chain glycosylphosphatidylinositol (GPI)-linked glycoprotein
• uPA-R was clustered as CD87 in the Fifth Human Leukocyte Differentiation Antigens Workshop
• It is expressed on neutrophils, monocytes, macrophages, dendritic cells, endothelial cells, activated T cells, fibroblasts, and smooth muscle
• CD87 plays a role in cell-associated fibrinolytic activity and tissue invasion
• This antibody may be useful in the study of myeloid cell differentiation
• This antibody is conjugated to BD Horizon™ BV605 which is part of the BD Horizon Brilliant™ Violet family of dyes
• With an Ex Max of 407nm and Em Max of 602nm, BD Horizon BV605 can be excited by a violet laser and detected with a standard 610/20nm filter set
• BD Horizon BV605 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an Em max at 605nm
• Due to the excitation of the acceptor dye by the green (532 nm) and yellow-green (561 nm) lasers, there will be significant spillover into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers
• BD Horizon BV605 conjugates are very bright, often exhibiting brightness equivalent to PE conjugates and can be used as a third color off of the violet laser
• BV605 is a tandem fluorochrome that combines BD Horizon BV421 and Cy™3.5
• These conjugates are very bright, exhibiting similar brightness to equivalent PE conjugates
• Due to the excitation of Cy3.5 by the green (532nm) and yellow-green (561nm) lasers, there will be significant spillover of the BD Horizon BV605 signal into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers.