BDB743170

CD337 (NKp30) Mouse anti-Human, Brilliant Violet 510, Clone: p30-15, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB743170-Each-of-1 In Stock ₹ 47,614.14

BDB743170 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

CD337 (NKp30)

Clone

p30-15

Conjugate

Brilliant Violet 510

Gene Alias

NCR3, Natural cytotoxicity triggering receptor 3, NKp30, MALS, LY117, 1C7

Immunogen

Horse NKp30 extracellular domain

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The p30-15 monoclonal antibody specifically binds to CD337, also known as NKp30, a receptor found on the surface of natural killer (NK) cells
  • NK cells are large lymphoid cells discovered because of their ability to recognize and kill abnormal cells such as tumor and virally infected cells
  • NK cell immune responses are regulated by a balance of activating and inhibitory signals generated by cell surface receptors
  • Inhibitory receptors recognize MHC class I molecules on normal cells producing a negative signal to the NK cell
  • Loss of MHC class I expression in infected or transformed cells results in the loss of this negative signal leading to NK cell activation
  • In concert with the loss of inhibitory signals, activation signals via NK receptors such as NKp30, NKp44, NKp46, NKG2D, and NKp80 mediate the activation of NK cells
  • NKp30 cooperates with NKp46 and/or NKp44 in the induction of NK cell-mediated cytotoxicity against the majority of target cells
  • The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 405nm and Em Max at 510nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50nm) filter set
  • BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser
  • BV510 is a polymer-based dye that is brighter than BD Horizon V500
  • Due to similar excitation and emission properties, BD Horizon BV510 and BD Horizon V500 cannot be used simultaneously.

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BD Biosciences

BDB743170

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Antigen:
CD337 (NKp30)

Clone:
p30-15

Conjugate:
Brilliant Violet 510

Gene Alias:
NCR3, Natural cytotoxicity triggering receptor 3, NKp30, MALS, LY117, 1C7

Immunogen:
Horse NKp30 extracellular domain

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB743171

--


Antigen:
CD337 (NKp30)

Clone:
p30-15

Conjugate:
Brilliant Violet 650

Gene Alias:
NCR3, Natural cytotoxicity triggering receptor 3, NKp30, MALS, LY117, 1C7

Immunogen:
Horse NKp30 extracellular domain

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB743175

--


Antigen:
IgG2b

Clone:
R12-3

Conjugate:
Brilliant Violet 510

Gene Alias:
Igh-3, gamma2b, Immunoglobulin heavy constant gamma 2B

Immunogen:
Pooled Mouse Ig

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Img

BD Biosciences

BDB743176

--


Antigen:
IgG2b

Clone:
R12-3

Conjugate:
Brilliant Violet 605

Gene Alias:
Igh-3, gamma2b, Immunoglobulin heavy constant gamma 2B

Immunogen:
Pooled Mouse Ig

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ