BDB743985
CD272 (BTLA) Mouse anti-Human, Brilliant Violet 510, Clone: J168-540, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB743985-Each-of-1 | In Stock | ₹ 47,400.24 |
BDB743985 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,400.24
GST (18%): ₹ 8,532.043
Total Price: ₹ 55,932.283
Antigen
CD272 (BTLA)
Clone
J168-540
Conjugate
Brilliant Violet 510
Gene Alias
BTLA1, B- and T-lymphocyte-associated protein
Immunogen
Human BTLA Recombinant Protein
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The J168-540 monoclonal antibody specifically binds to human CD272, also known as BTLA (B and T lymphocyte attenuator), an inhibitory receptor expressed in bone marrow and thymus on developing B and T cells
- In the periphery, BTLA is expressed by B cells, T cells, bone marrow-derived dendritic cells, and macrophages
- After T cell activation, BTLA appears to be expressed at higher levels on Th1 cell populations than in Th2 cell populations
- Upon binding the herpesvirus entry mediator (HVEM/LIGHT-R/CD270), CD272 undergoes tyrosine phosphorylation and inhibits T cell proliferation in a BTLA-dependent manner
- CD272 has structural similarities to two other lymphocyte inhibitory receptors, CTLA-4 and PD-1 and is a member of the CD28-like family of coreceptors
- Based on these observations, CD272 is considered to be a negative regulator of lymphocyte activation and/or function
- The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes
- With an Ex Max of 405nm and Em Max at 510nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50nm) filter set
- BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser
- BV510 is a polymer-based dye that is brighter than BD Horizon V500
- Due to similar excitation and emission properties, BD Horizon BV510 and BD Horizon V500 cannot be used simultaneously.
Compare Similar Items
Show Difference
Antigen: CD272 (BTLA)
Clone: J168-540
Conjugate: Brilliant Violet 510
Gene Alias: BTLA1, B- and T-lymphocyte-associated protein
Immunogen: Human BTLA Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD272 (BTLA)
Clone:
J168-540
Conjugate:
Brilliant Violet 510
Gene Alias:
BTLA1, B- and T-lymphocyte-associated protein
Immunogen:
Human BTLA Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD272 (BTLA)
Clone: J168-540
Conjugate: Brilliant Violet 605
Gene Alias: BTLA1, B- and T-lymphocyte-associated protein
Immunogen: Human BTLA Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD272 (BTLA)
Clone:
J168-540
Conjugate:
Brilliant Violet 605
Gene Alias:
BTLA1, B- and T-lymphocyte-associated protein
Immunogen:
Human BTLA Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD272 (BTLA)
Clone: J168-540
Conjugate: Brilliant Ultraviolet 395
Gene Alias: BTLA1, B- and T-lymphocyte-associated protein
Immunogen: Human BTLA Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD272 (BTLA)
Clone:
J168-540
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
BTLA1, B- and T-lymphocyte-associated protein
Immunogen:
Human BTLA Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Vβ 13 TCR
Clone: MR12-3
Conjugate: Brilliant Violet 421
Gene Alias: TCR V beta 13, TCR Vβ 13, TCR Vβ13, Vβ 13 T-cell Receptor
Immunogen: Not reported
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
Vβ 13 TCR
Clone:
MR12-3
Conjugate:
Brilliant Violet 421
Gene Alias:
TCR V beta 13, TCR Vβ 13, TCR Vβ13, Vβ 13 T-cell Receptor
Immunogen:
Not reported
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ