BDB743825
HVEM (CD270) Mouse anti-Human, Brilliant Violet 650, Clone: CW10, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB743825-Each-of-1 | In Stock | ₹ 47,400.24 |
BDB743825 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,400.24
GST (18%): ₹ 8,532.043
Total Price: ₹ 55,932.283
Antigen
HVEM (CD270)
Clone
CW10
Conjugate
Brilliant Violet 650
Gene Alias
TNFRSF14, HVEM, HVEA, LIGHTR, ATAR, TR2
Immunogen
Human Recombinant Protein
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The CW10 monoclonal antibody specifically binds to HVEM (Herpes virus entry mediator)
- HVEM is also known as CD270, Tumor necrosis factor receptor-like 2 (TR2), or LIGHT Receptor (LIGHT-R)
- CD270 is a type I transmembrane protein and member of the TNF Receptor superfamily
- It is encoded by TNFRSF14 (tumor necrosis factor receptor superfamily member 14)
- CD270 is expressed on T cells, B cells, NK cells, monocytes, granulocytes, and some dendritic cells
- CD270 binds to CD258/LIGHT, CD272/BTLA, and glycoprotein D of Herpes simplex viruses HSV-1 and HSV-2
- CD270-LIGHT interactions can reportedly transduce costimulatory signals for T cells whereas CD270-BTLA interactions can deliver inhibitory signals to T cells
- The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
- BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- However, the spillover can be corrected through compensation as with any other dye combination
- BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- BV650 will have moderate spillover into the BD Horizon™ BV711 detector.
Compare Similar Items
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Antigen: HVEM (CD270)
Clone: CW10
Conjugate: Brilliant Violet 650
Gene Alias: TNFRSF14, HVEM, HVEA, LIGHTR, ATAR, TR2
Immunogen: Human Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
HVEM (CD270)
Clone:
CW10
Conjugate:
Brilliant Violet 650
Gene Alias:
TNFRSF14, HVEM, HVEA, LIGHTR, ATAR, TR2
Immunogen:
Human Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: HVEM (CD270)
Clone: CW10
Conjugate: Brilliant Violet 786
Gene Alias: TNFRSF14, HVEM, HVEA, LIGHTR, ATAR, TR2
Immunogen: Human Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
HVEM (CD270)
Clone:
CW10
Conjugate:
Brilliant Violet 786
Gene Alias:
TNFRSF14, HVEM, HVEA, LIGHTR, ATAR, TR2
Immunogen:
Human Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: HVEM (CD270)
Clone: CW10
Conjugate: Brilliant Ultraviolet 395
Gene Alias: TNFRSF14, HVEM, HVEA, LIGHTR, ATAR, TR2
Immunogen: Human Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
HVEM (CD270)
Clone:
CW10
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
TNFRSF14, HVEM, HVEA, LIGHTR, ATAR, TR2
Immunogen:
Human Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Vα2 TCR
Clone: B20.1
Conjugate: Brilliant Violet 510
Gene Alias: T cell receptor alpha, variable region 2
Immunogen: Soluble αβ TCR from mouse cytotoxic T-cell clone KB5-C20
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a λ
Antigen:
Vα2 TCR
Clone:
B20.1
Conjugate:
Brilliant Violet 510
Gene Alias:
T cell receptor alpha, variable region 2
Immunogen:
Soluble αβ TCR from mouse cytotoxic T-cell clone KB5-C20
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a λ