BDB744053

CD161a Mouse anti-Rat, Brilliant Violet 711, Clone: 10/78., BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB744053-Each-of-1 In Stock ₹ 34,224.00

BDB744053 - Each of 1

₹ 34,224.00

In Stock

Quantity

1

Base Price: ₹ 34,224.00

GST (18%): ₹ 6,160.32

Total Price: ₹ 40,384.32

Antigen

CD161a

Clone

10/78.

Conjugate

Brilliant Violet 711

Gene Alias

CD161/Cd161, CD161a, Klrb1a, Nkrp1a/NKR-P1A, CD161b, Klrb1b, Nkrp1b/NKR-P1B

Immunogen

Not reported

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 κ

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Description

  • The 10/78 monoclonal antibody recognizes the rat CD161 proteins, CD161a (also known as, Klrb1a, or Nkrp1a/NKR-P1A), and CD161b (Klrb1b, Nkrp1b/NKR-P1B)
  • These type II transmembrane glycoproteins have an extracellular C-type lectin domain and thus belong to the C-type lectin superfamily
  • These CD161 proteins form ñ 60 kDa homodimers that are expressed on natural killer cells and subsets of T lymphocytes, activated monocytes, and dendritic cells
  • The 10/78 antibody competes with the previously-described 3.2.3 antibody for binding to these CD161 proteins
  • CD161 molecules are C-type lectin-like receptors that can either activate (CD161a) or inhibit (CD161b) effector leucocyte responses, eg, cytotoxicity or cytokine production, against target cells which express C-type lectin-like related (Clr) molecules
  • Although several members of the Klrb1 /gene family have been identified in the mouse and rat, only a single human KLRB1 /homolog has been discovered The antibody was conjugated to BD Horizon™ BV711 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 711nm
  • BD Horizon BV711 can be excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor™ 700-like dyes (eg, 712/20nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination
  • BV711 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 711 nm
  • This dye offers a very bright choice for the violet laser
  • Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
  • BV711 will also have moderate spillover into the BD Horizon Brilliant™ Violet 786 detector.

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BD Biosciences

BDB744053

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Antigen:
CD161a

Clone:
10/78.

Conjugate:
Brilliant Violet 711

Gene Alias:
CD161/Cd161, CD161a, Klrb1a, Nkrp1a/NKR-P1A, CD161b, Klrb1b, Nkrp1b/NKR-P1B

Immunogen:
Not reported

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

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BD Biosciences

BDB744055

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Antigen:
CD161a

Clone:
10/78.

Conjugate:
Brilliant Ultraviolet 395

Gene Alias:
CD161/Cd161, CD161a, Klrb1a, Nkrp1a/NKR-P1A, CD161b, Klrb1b, Nkrp1b/NKR-P1B

Immunogen:
Not reported

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

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Antigen:
CD205

Clone:
MMRI-7

Conjugate:
Brilliant Violet 510

Gene Alias:
DEC-205, Lymphocyte Antigen 75, LY75, Ly-75, CLEC13B, GP200-MR6

Immunogen:
__

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

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Antigen:
CD205

Clone:
MMRI-7

Conjugate:
Brilliant Violet 650

Gene Alias:
DEC-205, Lymphocyte Antigen 75, LY75, Ly-75, CLEC13B, GP200-MR6

Immunogen:
__

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ