BDB744073

Disialoganglioside GD2 Mouse anti-Human, Brilliant Violet 786, Clone: 14.G2a, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB744073-Each-of-1 In Stock ₹ 47,400.24

BDB744073 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

Disialoganglioside GD2

Clone

14.G2a

Conjugate

Brilliant Violet 786

Gene Alias

GD2, Disialoganglioside GD2, Ganglioside GD2

Immunogen

LAN-1 human neuroblastoma cells

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a

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Description

  • Gangliosides are sialic-acid bearing glycolipids that are expressed on the surface of all mammalian cells, and are likely involved in mediating cell-substratum interactions
  • They are important target antigens for antibody dependent cellular cytotoxicity (ADCC) of human melanoma and neuroblastoma cells
  • Human melanoma cells produce gangliosides, designated as GD2 and GD3 which are deposited in the subtratum-attached material, and may play a significant role in the melanoma metastatic phenotype
  • Clone 14.G2a specifically reacts with human and mouse GD2 ganglioside
  • LAN-1 human neuroblastoma cells were used as immunogen
  • Clone 14.G2a is an isotype switch variant selected from the parental IgG3-producing hybridoma 14.18 and has identical reactivity as the parental antibody
  • Clone 14.G2a is routinely tested by flow cytometry using M21 human melanoma cells The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm
  • BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter)
  • BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm
  • BV786 offers a bright choice for the 6th detector off the violet laser.

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Show Difference

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BD Biosciences

BDB744073

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Antigen:
Disialoganglioside GD2

Clone:
14.G2a

Conjugate:
Brilliant Violet 786

Gene Alias:
GD2, Disialoganglioside GD2, Ganglioside GD2

Immunogen:
LAN-1 human neuroblastoma cells

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a

Img

BD Biosciences

BDB744074

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Antigen:
CD31

Clone:
MBC 78.2 (also known as PECAM-1.2; 1.2)

Conjugate:
Brilliant Violet 421

Gene Alias:
PECAM-1, PECAM1, EndoCAM, GPIIA'

Immunogen:
Human CD31

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB744075

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Antigen:
CD31

Clone:
MBC 78.2 (also known as PECAM-1.2; 1.2)

Conjugate:
Brilliant Violet 510

Gene Alias:
PECAM-1, PECAM1, EndoCAM, GPIIA'

Immunogen:
Human CD31

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB744077

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Antigen:
CD31

Clone:
MBC 78.2 (also known as PECAM-1.2; 1.2)

Conjugate:
Brilliant Violet 650

Gene Alias:
PECAM-1, PECAM1, EndoCAM, GPIIA'

Immunogen:
Human CD31

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ