BDB744098
CD178 Mouse anti-Human, Brilliant Violet 510, Clone: NOK-1, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB744098-Each-of-1 | In Stock | ₹ 49,528.50 |
BDB744098 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,528.50
GST (18%): ₹ 8,915.13
Total Price: ₹ 58,443.63
Antigen
CD178
Clone
NOK-1
Conjugate
Brilliant Violet 510
Gene Alias
Fas ligand, FASL, FASLG, CD95 ligand, CD95L, CD95-L, TNFSF6, APTL, APT1LG1
Immunogen
Mouse T lymphoma cells (L5178Y) expressing human FasL
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1
Related Products
Description
- The NOK-1 monoclonal antibody specifically recognizes CD178
- Fas (CD95; APO-1) is a 45 kDa cell surface protein that mediates apoptosis when cross-linked with agonistic anti-Fas antibodies or by Fas ligand (FasL; CD178)
- Fas belongs to the TNF (Tumor Necrosis Factor)/NGF (Nerve Growth Factor) receptor family, and is expressed in various tissues and cells including the thymus, liver, ovary and lung
- CD178 (FasL), a member of the TNF cytokine family, induces apoptosis by binding to Fas, its cell-surface receptor
- FasL may exist as either membrane bound or soluble forms and is expressed by activated T and NK cells
- FasL may also be constitutively expressed in some immunologically privileged sites, e.g., eye and testis
- Fas and FasL play an important role in the induction of apoptosis, and thus regulate a variety of immunological responses
- The NOK-1 antibody clone has been reported to recognize human FasL, recognizing both the membrane bound (FasL) and soluble (sFasL) forms
- It is reported that the epitope for NOK-1 has been mapped to the COOH-terminus of FasL, at the region implicated in Fas binding
- FasL and sFasL have been reported to migrate at reduced molecular weights of 40 and 26 kDa, respectively
- However, the molecular weights observed in a particular sample may vary according to FasL and sFasL glycosylation and breakdown patterns as described in the literature
- The NOK-1 antibody clone is not recommended for the Western blot application
- The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes
- With an Ex Max of 405nm and Em Max at 510nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50nm) filter set
- BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser
- BV510 is a polymer-based dye that is brighter than BD Horizon V500
- Due to similar excitation and emission properties, BD Horizon BV510 and BD Horizon V500 cannot be used simultaneously.
Compare Similar Items
Show Difference
Antigen: CD178
Clone: NOK-1
Conjugate: Brilliant Violet 510
Gene Alias: Fas ligand, FASL, FASLG, CD95 ligand, CD95L, CD95-L, TNFSF6, APTL, APT1LG1
Immunogen: Mouse T lymphoma cells (L5178Y) expressing human FasL
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1
Antigen:
CD178
Clone:
NOK-1
Conjugate:
Brilliant Violet 510
Gene Alias:
Fas ligand, FASL, FASLG, CD95 ligand, CD95L, CD95-L, TNFSF6, APTL, APT1LG1
Immunogen:
Mouse T lymphoma cells (L5178Y) expressing human FasL
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1
Antigen: CD178
Clone: NOK-1
Conjugate: Brilliant Violet 605
Gene Alias: Fas ligand, FASL, FASLG, CD95 ligand, CD95L, CD95-L, TNFSF6, APTL, APT1LG1
Immunogen: Mouse T lymphoma cells (L5178Y) expressing human FasL
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1
Antigen:
CD178
Clone:
NOK-1
Conjugate:
Brilliant Violet 605
Gene Alias:
Fas ligand, FASL, FASLG, CD95 ligand, CD95L, CD95-L, TNFSF6, APTL, APT1LG1
Immunogen:
Mouse T lymphoma cells (L5178Y) expressing human FasL
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1
Antigen: CD178
Clone: NOK-1
Conjugate: Brilliant Violet 650
Gene Alias: Fas ligand, FASL, FASLG, CD95 ligand, CD95L, CD95-L, TNFSF6, APTL, APT1LG1
Immunogen: Mouse T lymphoma cells (L5178Y) expressing human FasL
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1
Antigen:
CD178
Clone:
NOK-1
Conjugate:
Brilliant Violet 650
Gene Alias:
Fas ligand, FASL, FASLG, CD95 ligand, CD95L, CD95-L, TNFSF6, APTL, APT1LG1
Immunogen:
Mouse T lymphoma cells (L5178Y) expressing human FasL
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1
Antigen: CD178
Clone: NOK-1
Conjugate: Brilliant Violet 711
Gene Alias: Fas ligand, FASL, FASLG, CD95 ligand, CD95L, CD95-L, TNFSF6, APTL, APT1LG1
Immunogen: Mouse T lymphoma cells (L5178Y) expressing human FasL
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1
Antigen:
CD178
Clone:
NOK-1
Conjugate:
Brilliant Violet 711
Gene Alias:
Fas ligand, FASL, FASLG, CD95 ligand, CD95L, CD95-L, TNFSF6, APTL, APT1LG1
Immunogen:
Mouse T lymphoma cells (L5178Y) expressing human FasL
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1