BDB744330

Vβ 8.1, 8.2 TCR Mouse anti-Mouse, Brilliant Violet 510, Clone: MR5-2, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB744330-Each-of-1 In Stock ₹ 34,052.88

BDB744330 - Each of 1

₹ 34,052.88

In Stock

Quantity

1

Base Price: ₹ 34,052.88

GST (18%): ₹ 6,129.518

Total Price: ₹ 40,182.398

Antigen

Vβ 8.1, 8.2 TCR

Clone

MR5-2

Conjugate

Brilliant Violet 510

Gene Alias

TCR V beta 8.1, TCR V beta 8.2

Immunogen

C57BL/6 mouse helper T-cell clone OI6

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2a κ

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Description

  • The MR5-2 antibody reacts with the V β 8.1 and V β 8.2 T-cell Receptors (TCR), but not the V β 8.3 TCR, of mice having the b haplotype ( e.g ., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C58, DBA/1, DBA/2) of the Tcrb gene complex
  • The Tcrb-V8 subfamily gene loci are deleted in mice having the a ( e.g ., C57BR, C57L, SJL, SWR) or c ( e.g., RIII) haplotype
  • V β 8.1 TCR-bearing T lymphocytes are clonally eliminated in mice expressing superantigen encoded by the Mtv-7 (Mls-1a, Mlsa), provirus ( e.g., AKR, CBA/J, C58, DBA/2), and activation or elimination of V β 8.1 TCR-expressing T cells by this determinant is partially dependent upon presentation by I-E
  • Mtv-43 (e.g., MA/MyJ), Mtv-44 (e.g., NZW), and/or exogenous MMTV-SW superantigens also cause incomplete elimination of V β 8.1 TCR-bearing T cells
  • In addition to expression on conventional T lymphocytes, V β 8.2 is the predominant β chain of the TCR on NK-T cells
  • Staphylococcal enterotoxin B, in association with antigen presenting cells expressing I-A and/or I-E, stimulates lymphocytes bearing V β 8 TCR and selectively eliminates those T cells in vivo
  • Plate-bound MR5-2 antibody activates V β 8.1 or 8.2 TCR-bearing T lymphocytes
  • The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 405nm and Em Max at 510nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50nm) filter set
  • BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser
  • BV510 is a polymer-based dye that is brighter than BD Horizon V500
  • Due to similar excitation and emission properties, BD Horizon BV510 and BD Horizon V500 cannot be used simultaneously.

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Show Difference

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BD Biosciences

BDB744330

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Antigen:
Vβ 8.1, 8.2 TCR

Clone:
MR5-2

Conjugate:
Brilliant Violet 510

Gene Alias:
TCR V beta 8.1, TCR V beta 8.2

Immunogen:
C57BL/6 mouse helper T-cell clone OI6

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Img

BD Biosciences

BDB744331

--


Antigen:
Vβ 8.1, 8.2 TCR

Clone:
MR5-2

Conjugate:
Brilliant Violet 605

Gene Alias:
TCR V beta 8.1, TCR V beta 8.2

Immunogen:
C57BL/6 mouse helper T-cell clone OI6

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Img

BD Biosciences

BDB744332

--


Antigen:
Vβ 8.1, 8.2 TCR

Clone:
MR5-2

Conjugate:
Brilliant Violet 650

Gene Alias:
TCR V beta 8.1, TCR V beta 8.2

Immunogen:
C57BL/6 mouse helper T-cell clone OI6

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Img

BD Biosciences

BDB744333

--


Antigen:
Vβ 8.1, 8.2 TCR

Clone:
MR5-2

Conjugate:
Brilliant Violet 711

Gene Alias:
TCR V beta 8.1, TCR V beta 8.2

Immunogen:
C57BL/6 mouse helper T-cell clone OI6

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ