BDB744335
Vβ 8.1, 8.2 TCR Mouse anti-Mouse, BUV395, Clone: MR5-2, BD Optibuild™
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB744335-Each-of-1 | In Stock | ₹ 34,052.88 |
BDB744335 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,052.88
GST (18%): ₹ 6,129.518
Total Price: ₹ 40,182.398
Antigen
Vβ 8.1, 8.2 TCR
Clone
MR5-2
Conjugate
Brilliant Ultraviolet 395
Gene Alias
TCR V beta 8.1, TCR V beta 8.2
Immunogen
C57BL/6 mouse helper T-cell clone OI6
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2a κ
Related Products
Description
- The MR5-2 antibody reacts with the V β 8.1 and V β 8.2 T-cell Receptors (TCR), but not the V β 8.3 TCR, of mice having the b haplotype ( e.g ., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C58, DBA/1, DBA/2) of the Tcrb gene complex
- The Tcrb-V8 subfamily gene loci are deleted in mice having the a ( e.g ., C57BR, C57L, SJL, SWR) or c ( e.g., RIII) haplotype
- V β 8.1 TCR-bearing T lymphocytes are clonally eliminated in mice expressing superantigen encoded by the Mtv-7 (Mls-1a, Mlsa), provirus ( e.g., AKR, CBA/J, C58, DBA/2), and activation or elimination of V β 8.1 TCR-expressing T cells by this determinant is partially dependent upon presentation by I-E
- Mtv-43 (e.g., MA/MyJ), Mtv-44 (e.g., NZW), and/or exogenous MMTV-SW superantigens also cause incomplete elimination of V β 8.1 TCR-bearing T cells
- In addition to expression on conventional T lymphocytes, V β 8.2 is the predominant β chain of the TCR on NK-T cells
- Staphylococcal enterotoxin B, in association with antigen presenting cells expressing I-A and/or I-E, stimulates lymphocytes bearing V β 8 TCR and selectively eliminates those T cells in vivo
- Plate-bound MR5-2 antibody activates V β 8.1 or 8.2 TCR-bearing T lymphocytes
- The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
- This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
- With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter
- BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences
- With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter
- This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.
Compare Similar Items
Show Difference
Antigen: Vβ 8.1, 8.2 TCR
Clone: MR5-2
Conjugate: Brilliant Ultraviolet 395
Gene Alias: TCR V beta 8.1, TCR V beta 8.2
Immunogen: C57BL/6 mouse helper T-cell clone OI6
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
Vβ 8.1, 8.2 TCR
Clone:
MR5-2
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
TCR V beta 8.1, TCR V beta 8.2
Immunogen:
C57BL/6 mouse helper T-cell clone OI6
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: F4/80-Like Receptor
Clone: 6F12
Conjugate: Brilliant Violet 650
Gene Alias: Fire, Emr4, EGF-like module receptor 4, D17Ertd479e, Egf-tm7
Immunogen: CHO cells expressing recombinant FIRE fusion protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
F4/80-Like Receptor
Clone:
6F12
Conjugate:
Brilliant Violet 650
Gene Alias:
Fire, Emr4, EGF-like module receptor 4, D17Ertd479e, Egf-tm7
Immunogen:
CHO cells expressing recombinant FIRE fusion protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: F4/80-Like Receptor
Clone: 6F12
Conjugate: Brilliant Ultraviolet 395
Gene Alias: Fire, Emr4, EGF-like module receptor 4, D17Ertd479e, Egf-tm7
Immunogen: CHO cells expressing recombinant FIRE fusion protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
F4/80-Like Receptor
Clone:
6F12
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
Fire, Emr4, EGF-like module receptor 4, D17Ertd479e, Egf-tm7
Immunogen:
CHO cells expressing recombinant FIRE fusion protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: CD150
Clone: A12
Conjugate: Brilliant Violet 510
Gene Alias: SLAMF1; Signaling lymphocytic activation molecule; SLAM; SLAF1; IPO-3
Immunogen: Activated Human Peripheral Blood Mononuclear Cells
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon BV510 under optimal conditions that minimize unconjugated dye and antibody.
Classification: Monoclonal
Concentration: __
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD150
Clone:
A12
Conjugate:
Brilliant Violet 510
Gene Alias:
SLAMF1; Signaling lymphocytic activation molecule; SLAM; SLAF1; IPO-3
Immunogen:
Activated Human Peripheral Blood Mononuclear Cells
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon BV510 under optimal conditions that minimize unconjugated dye and antibody.
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ