FEMA549757

CD163 Recombinant Rabbit Monoclonal Antibody (7B2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549757-Each-of-1 In Stock ₹ 35,764.08

FEMA549757 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

CD163

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q86VB7

Gene Symbols

CD163

Immunogen

A synthesized peptide

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)

Clone

7B2

Conjugate

Unconjugated

Gene

CD163

Gene Alias

CD163, CD163 antigen, CD163 molecule, CD163v2, CD163v3, Hemoglobin scavenger receptor, M130, macrophage-associated antigen, MM130, putative CD163 antigen, SCARI1, Scavenger receptor cysteine-rich type 1 protein M130, sCD163, Soluble CD163, Soluble sCD163

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9332

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • CD163 (M130 antigen, Ber-Mac3, Ki-M8, SM4) is a 130 kDa membrane glycoprotein, a member of the scavenger receptor cysteine-rich superfamily, and a receptor for the hemoglobin-haptoglobin complex
  • CD163 protects tissues from free hemoglobin-mediated oxidative damage, and may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme
  • CD163 is expressed exclusively on the cell surface of human monocytes and macrophages that evolve predominantly in the late phase of inflammation
  • Specifically, CD163 is present on all circulating monocytes and most tissue macrophages except those found in the mantle zone and germinal centers of lymphoid follicles, interdigitating reticulum cells and Langerhan's cells
  • CD163 is present on all CD14 positive monocytes, most CD64 positive monocytes, and shows higher expression on CD16 positive monocytes
  • CD163 is upregulated on mononuclear phagocytes by IL-10, IL-6 and dexamethasone
  • Lipopolysaccharide (LPS) and phorbol myristate acetate (PMA) both induce shedding of CD163 from the cell surface into plasma or cell supernatant
  • CD163 binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner, and exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP1S phenotype
  • Further, CD163 also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA549757

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Antigen:
CD163

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q86VB7

Gene Symbols:
CD163

Immunogen:
A synthesized peptide

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)

Clone:
7B2

Conjugate:
Unconjugated

Gene:
CD163

Gene Alias:
CD163, CD163 antigen, CD163 molecule, CD163v2, CD163v3, Hemoglobin scavenger receptor, M130, macrophage-associated antigen, MM130, putative CD163 antigen, SCARI1, Scavenger receptor cysteine-rich type 1 protein M130, sCD163, Soluble CD163, Soluble sCD163

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9332

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549758

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Antigen:
CD97

Classification:
Recombinant Monoclonal

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P48960

Gene Symbols:
ADGRE5, CD97

Immunogen:
A synthesized peptide

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
3A7

Conjugate:
Unconjugated

Gene:
CD97

Gene Alias:
AA409984, Adgre5, adhesion G protein-coupled receptor E5, Cd97, CD97 antigen, CD97 antigen subunit alpha, CD97 antigen subunit beta, CD97 molecule, EGF-TM7 receptor, leukocyte antigen CD97, seven transmembrane helix receptor, seven-span transmembrane protein, seven-transmembrane, heterodimeric receptor associated with inflammation, TM7LN1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
976

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549761

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Antigen:
Phospho-c-Myc (Thr58, Ser62)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P01106

Gene Symbols:
MYC

Immunogen:
A synthesized peptide derived from human Phospho-MYC (T58+S62)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
4E9

Conjugate:
Unconjugated

Gene:
MYC

Gene Alias:
AU016757, Avian myelocytomatosis viral (v-myc) oncogene homolog, avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, class E basic helix-loop-helix protein 39, cmyc, c-Myc, c-myc epitope tag, c-myc proto-oncogene, mMyc, MRTL, Myc, Myc protein, Myc proto-oncogene protein, MYC proto-oncogene, bHLH transcription factor, Myc2, MYCC, myc-related translation/localization regulatory factor, myelocytomatosis oncogene, myelocytomatosis viral oncogene homolog, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene-like protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4609

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549763

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Antigen:
Phospho-STAT5 alpha (Tyr694)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P42229

Gene Symbols:
STAT5A

Immunogen:
A synthesized peptide derived from human Phospho-STAT5A (Y694)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
3F1

Conjugate:
Unconjugated

Gene:
STAT5A

Gene Alias:
AA959963, mammary gland factor, mammary gland factor STAT5A, mammary gland factor, transcription factor, Mgf, Mpf, signal transducer and activator of transcription 5, signal transducer and activator of transcription 5a, signal transducer and activator of transcription factor 5A, STAT, STAT5, STAT5A, STAT5A, Mammary Gland Factor, STAT5A/MGF, STAT5B, STATA5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6776

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG