FEMA549770

Phospho-JAK2 (Tyr1007, Tyr1008) Recombinant Rabbit Monoclonal Antibody (1A4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549770-Each-of-1 In Stock ₹ 35,764.08

FEMA549770 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

Phospho-JAK2 (Tyr1007, Tyr1008)

Classification

Recombinant Monoclonal

Concentration

0.25 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

O60674

Gene Symbols

JAK2

Immunogen

A synthesized peptide derived from human Phospho-JAK2 (Y1007 + Y1008)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

1A4

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3717

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera
  • This kinase contains the catalytic domain (JH1) of JAK2
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting JAK2 can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

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Thermo Scientific

FEMA549770

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Antigen:
Phospho-JAK2 (Tyr1007, Tyr1008)

Classification:
Recombinant Monoclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
O60674

Gene Symbols:
JAK2

Immunogen:
A synthesized peptide derived from human Phospho-JAK2 (Y1007 + Y1008)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
1A4

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3717

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549775

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Antigen:
Phospho-AKT1 (Ser473)

Classification:
Recombinant Monoclonal

Concentration:
0.8 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P31749

Gene Symbols:
AKT1

Immunogen:
A synthesized peptide derived from human Phospho-AKT1 (Ser473)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
4H12

Conjugate:
Unconjugated

Gene:
AKT1

Gene Alias:
Akt, Akt kinase, AKT serine/threonine kinase 1, Akt/PKB, akt1, AKT1 kinase, AKT1m, Akt1m protein, Akt1-PA, Akt1-PB, Akt1-PC, Akt1-PD, Akt1-PE, CAKT, C-AKT, CG4006, CG4006-PA, CG4006-PB, CG4006-PC, CG4006-PD, CG4006-PE, CWS6, dAkt, D-Akt, dAkt kinase, dAKT/dPKB, dAkt/PKB, DAKT1, DAKT1/PKB, Dmel\CG4006, Dmel_CG4006, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, l(3)04226, l(3)89Bq, murine thymoma viral (v-akt) oncogene homolog 1, pAkt, P-AKT, PKB, PKB alpha, PKB beta, PKB gamma, PKB/AKT, PKB/dAKT, PKBalpha, PKB-ALPHA, PKBG, PRKBA, protein kinase B, Protein kinase B alpha, protein kinase B-alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC protein kinase alpha RAC-PK alpha, RAC serine/threonine protein kinase, RAC serine/threonine-protein kinase, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RacPK, RAC-PK-alpha, RAC-PK-beta, RAC-PK-gamma, related to A and C kinases, related to PKA to PKC protein kinases, related to the A and C kinases, SD10374p, serine/threonine protein kinase, serine-threonine protein kinase, Thymoma viral proto-oncogene, thymoma viral proto-oncogene 1, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
207

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549779

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Antigen:
Phospho-alpha Synuclein (Ser129)

Classification:
Recombinant Monoclonal

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P37840

Gene Symbols:
SNCA

Immunogen:
A synthesized peptide derived from human Phospho-SNCA (S129)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
4G3

Conjugate:
Unconjugated

Gene:
SNCA

Gene Alias:
Alpha synuclein, alphaSYN, alpha-synuclein, NACP, non A-beta component of AD amyloid, non-A beta component of AD amyloid, non-A4 component of amyloid, Non-A4 component of amyloid precursor, PARK1, PARK4, PD1, Snca, Syn, synuclein alpha, synuclein alpha-140, synuclein, alpha, synuclein, alpha (non A4 component of amyloid precursor)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6622

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549780

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Antigen:
Phospho-MLKL (Ser358)

Classification:
Recombinant Monoclonal

Concentration:
1.6 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q8NB16

Gene Symbols:
Mlkl

Immunogen:
A synthesized peptide derived from human Phospho-MLKL (S358)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
4A6

Conjugate:
Unconjugated

Gene:
Mlkl

Gene Alias:
9130019I15Rik, hMLKL, mixed lineage kinase domain like pseudokinase, mixed lineage kinase domain-like, mixed lineage kinase domain-like protein, Mlkl, rCG51567-like

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
197259

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG