FEMA549862

JAK3 Recombinant Rabbit Monoclonal Antibody (1C7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549862-Each-of-1 In Stock ₹ 35,764.08

FEMA549862 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

JAK3

Classification

Recombinant Monoclonal

Concentration

1.5 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P52333

Gene Symbols

JAK3

Immunogen

A synthesized peptide derived from human JAK3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Clone

1C7

Conjugate

Unconjugated

Gene

JAK3

Gene Alias

Breast-JAK3, fae, JAK3, JAK-3, JAK3_HUMAN, JAK3B, JAKL, Janus kinase 3, Janus kinase 3 (a protein tyrosine kinase, leukocyte), Janus kinase 3 protein-tyrosine kinase, Janus kinase 3, protein-tyrosine kinase, L JAK, Leukocyte janus kinase, LJAK, L-JAK, RATJAK3, Tyrosine-protein kinase JAK3, wil

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3718

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • Janus kinase 3 (JAK3) phosphorylates members of the STAT (signal transduction and activators of transcription) family
  • JAK3 is predominantly expressed in immune cells and transduces a signal in response to activation of interleukin receptors
  • In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • However, active JAK1 may be required for complex responses
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex.

Compare Similar Items

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Thermo Scientific

FEMA549862

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Antigen:
JAK3

Classification:
Recombinant Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P52333

Gene Symbols:
JAK3

Immunogen:
A synthesized peptide derived from human JAK3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
1C7

Conjugate:
Unconjugated

Gene:
JAK3

Gene Alias:
Breast-JAK3, fae, JAK3, JAK-3, JAK3_HUMAN, JAK3B, JAKL, Janus kinase 3, Janus kinase 3 (a protein tyrosine kinase, leukocyte), Janus kinase 3 protein-tyrosine kinase, Janus kinase 3, protein-tyrosine kinase, L JAK, Leukocyte janus kinase, LJAK, L-JAK, RATJAK3, Tyrosine-protein kinase JAK3, wil

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3718

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549864

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Antigen:
KIF11

Classification:
Recombinant Monoclonal

Concentration:
0.53 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P52732

Gene Symbols:
KIF11

Immunogen:
A synthesized peptide derived from human Eg5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
1G11

Conjugate:
Unconjugated

Gene:
KIF11

Gene Alias:
Eg5, HKSP, KIF11, Kif8, Kifl1, Kines, kinesin 11, kinesin family member 11, kinesin-like 1, kinesin-like protein 1, Kinesin-like protein KIF11, kinesin-like spindle protein HKSP, Kinesin-related motor protein Eg5, Knsl1, MCLMR, Thyroid receptor-interacting protein 5, TR-interacting protein 5, TRIP5, TRIP-5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3832

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549866

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Antigen:
DDX5

Classification:
Recombinant Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P17844, Q61656

Gene Symbols:
DDX5

Immunogen:
A synthesized peptide derived from human DDX5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
2C3

Conjugate:
Unconjugated

Gene:
DDX5

Gene Alias:
2600009A06Rik, ATP-dependent RNA helicase DDX5, DDX5, ddx5 gene protein, D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 5, DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 5, DEAD (Asp-Glu-Ala-Asp) box helicase 5, DEAD (Asp-Glu-Ala-Asp) box polypeptide 5, DEAD box protein 5, DEAD box RNA helicase DEAD1, DEAD box-5, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD), DEAD-box helicase 5, DKFZp434E109, DKFZp686J01190, G17P1, HELR, Hlr1, HUMP68, mDEAD1, MGC118083, p68, p68 RNA helicase, PCR product with interspecies-compatible primers, probable ATP-dependent RNA helicase DDX5, RNA helicase p68, RP23-247J12.4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13207, 1655

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549867

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Antigen:
LOXL2

Classification:
Recombinant Monoclonal

Concentration:
0.23 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
B5DF27, P58022, Q9Y4K0

Gene Symbols:
LOXL2

Immunogen:
A synthesized peptide derived from human LOXL2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
2E5

Conjugate:
Unconjugated

Gene:
LOXL2

Gene Alias:
1110004B06Rik, 4930526G11Rik, 9430067E15Rik, LOR2, Loxl2, Lysyl oxidase homolog 2, lysyl oxidase homolog 2, LOW QUALITY PROTEIN: lysyl oxidase homolog 2, lysyl oxidase like 2, lysyl oxidase related 2, lysyl oxidase-like 2, lysyl oxidase-like 2 delta e13, lysyl oxidase-like 2 protein, lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, lysyl oxidase-related protein WS9-14, WS9-14

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
290350, 4017, 94352

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG