FEMA549901

JAK2 Recombinant Rabbit Monoclonal Antibody (10B6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549901-Each-of-1 In Stock ₹ 35,764.08

FEMA549901 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

JAK2

Classification

Recombinant Monoclonal

Concentration

1.5 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

O60674

Gene Symbols

JAK2

Immunogen

A synthesized peptide derived from human JAK2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunocytochemistry

Clone

10B6

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3717

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera
  • This kinase contains the catalytic domain (JH1) of JAK2
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting JAK2 can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

Compare Similar Items

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Thermo Scientific

FEMA549901

--


Antigen:
JAK2

Classification:
Recombinant Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
O60674

Gene Symbols:
JAK2

Immunogen:
A synthesized peptide derived from human JAK2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry

Clone:
10B6

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3717

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA549902

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Antigen:
TLR5

Classification:
Recombinant Monoclonal

Concentration:
1.2 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
O60602

Gene Symbols:
TLR5

Immunogen:
A synthesized peptide derived from human TLR5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
10D8

Conjugate:
Unconjugated

Gene:
TLR5

Gene Alias:
FLJ10052, MELIOS, MGC126430, MGC126431, RP11-239E10.1, SLE1, SLEB1, systemic lupus erythematosus susceptibility 1, TIL3, Tlr5, toll like receptor 5, Toll/interleukin-1 receptor-like protein 3, toll-like receptor 5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7100

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

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FEMA549903

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Antigen:
CA125

Classification:
Recombinant Monoclonal

Concentration:
0.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q8WXI7

Gene Symbols:
MUC16

Immunogen:
A synthesized peptide derived from human MUC16

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
10E9

Conjugate:
Unconjugated

Gene:
MUC16

Gene Alias:
1110008I14Rik, Ca125, CA-125, CA125 ovarian cancer antigen, ca-ovarian, FLJ14303, Gm1480, MUC16, MUC-16, mucin 16, mucin 16, cell surface associated, mucin-16, Ovarian cancer-related tumor marker CA125, ovarian carcinoma antigen CA125, RGD1308422

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
94025

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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Thermo Scientific

FEMA549904

--


Antigen:
CA125

Classification:
Recombinant Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q8WXI7

Gene Symbols:
MUC16

Immunogen:
A synthesized peptide derived from human CA-125 (MUC16)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
10F10

Conjugate:
Unconjugated

Gene:
MUC16

Gene Alias:
1110008I14Rik, Ca125, CA-125, CA125 ovarian cancer antigen, ca-ovarian, FLJ14303, Gm1480, MUC16, MUC-16, mucin 16, mucin 16, cell surface associated, mucin-16, Ovarian cancer-related tumor marker CA125, ovarian carcinoma antigen CA125, RGD1308422

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
94025

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG