FEMA550109
tPA Recombinant Rabbit Monoclonal Antibody (32B1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550109-Each-of-1 | In Stock | ₹ 35,764.08 |
FEMA550109 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,764.08
GST (18%): ₹ 6,437.534
Total Price: ₹ 42,201.614
Antigen
tPA
Classification
Recombinant Monoclonal
Concentration
3 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P00750
Gene Symbols
PLAT
Immunogen
A synthesized peptide derived from Human PLAT
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry
Clone
32B1
Conjugate
Unconjugated
Gene
PLAT
Gene Alias
3.4.21.68, Alteplase, AU020998, AW212668, D8Ertd2e, PATISS, plasminogen activator, tissue, plasminogen activator, tissue type, plasminogen/activator kringle, PLAT, Reteplase, serine protease, t plasminogen activator, tissue plasminogen activator, tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, TPA, t-PA, t-plasminogen activator
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5327
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- TPA converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen
- By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physio pathological events
- It specifically cleaves the Arg- -Val bond in plasminogen to form plasmin, and is comprised of a heterodimer of chain A and chain B held by a disulfide bond
- TPA binds to fibrin with high affinity
- This interaction leads to an increase in the catalytic efficiency of the enzyme between 100-and 1000-fold, due to an increase in affinity for plasminogen
- Similarly, binding to heparin increases the activation of plasminogen
- Binding to laminin and fibronectin has also been demonstrated
- TPA also binds to mannose receptor and the low-density lipoprotein receptor-related protein (LRP1)
- These proteins are involved in TPA clearance
- TPA binds to annexin II and to cytokeratin 8
- As yet unidentified interactions on endothelial cells and vascular smooth muscle cells (VSMC) lead to a 100-fold stimulation of plasminogen activation
- In addition, binding to VSMC reduces TPA inhibition by PAI-1 by 30-fold.
Compare Similar Items
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Antigen: tPA
Classification: Recombinant Monoclonal
Concentration: 3 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P00750
Gene Symbols: PLAT
Immunogen: A synthesized peptide derived from Human PLAT
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry
Clone: 32B1
Conjugate: Unconjugated
Gene: PLAT
Gene Alias: 3.4.21.68, Alteplase, AU020998, AW212668, D8Ertd2e, PATISS, plasminogen activator, tissue, plasminogen activator, tissue type, plasminogen/activator kringle, PLAT, Reteplase, serine protease, t plasminogen activator, tissue plasminogen activator, tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, TPA, t-PA, t-plasminogen activator
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5327
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
tPA
Classification:
Recombinant Monoclonal
Concentration:
3 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P00750
Gene Symbols:
PLAT
Immunogen:
A synthesized peptide derived from Human PLAT
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry
Clone:
32B1
Conjugate:
Unconjugated
Gene:
PLAT
Gene Alias:
3.4.21.68, Alteplase, AU020998, AW212668, D8Ertd2e, PATISS, plasminogen activator, tissue, plasminogen activator, tissue type, plasminogen/activator kringle, PLAT, Reteplase, serine protease, t plasminogen activator, tissue plasminogen activator, tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, TPA, t-PA, t-plasminogen activator
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5327
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: IL-8 (CXCL8)
Classification: Recombinant Monoclonal
Concentration: 1.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P10145
Gene Symbols: CXCL8
Immunogen: A synthesized peptide derived from Human IL8
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry
Clone: 33A9
Conjugate: Unconjugated
Gene: CXCL8
Gene Alias: (Ala-IL-8)77, (Ser-IL-8)72, Alveolar macrophage chemotactic factor I, alveolar macrophage-derived chemotactic factor-I, AMCF-I, ANX7, beta endothelial cell-derived neutrophil activating peptide, beta-thromboglobulin-like protein, chemokine (C-X-C motif) ligand 8, C-X-C motif chemokine 8, C-X-C motif chemokine ligand 8, CXCL8, cytokine 8, emoctakin, GCP/IL-8 protein I, GCP/IL-8 protein II, GCP/IL-8 protein III, GCP/IL-8 protein IV, GCP/IL-8 protein V, GCP/IL-8 protein VI, GCP1, GCP-1, Granulocyte chemotactic protein 1, IL8, IL-8, IL-8(1-77), IL-8(5-77), IL-8(6-77), IL-8(7-77), IL-8(8-77), IL-8(9-77), IL8/NAP1 form I, IL8/NAP1 form II, IL8/NAP1 form III, IL8/NAP1 form IV, IL8/NAP1 form V, IL8/NAP1 form VI, ILN, Interleukin, interleukin 8, Interleukin8, interleukin-8, interleuklin-8 precursor, LECT, LUCT, lung giant cell carcinoma-derived chemotactic protein, lymphocyte derived neutrophil activating peptide, Lymphocyte-derived neutrophil-activating factor, LYNAP, MDNCF, MDNCF-a, MDNCF-b, MDNCF-c, MONAP, Monocyte-derived neutrophil chemotactic factor, monocyte-derived neutrophil-activating peptide, NAF, NAP1, NAP-1, neutrophil activating peptide 1, neutrophil and T-lymphocyte chemotactic and activating factor, Neutrophil attractant/activation protein 1, neutrophil attractant/activation protein-1, Neutrophil-activating factor, neutrophil-activating peptide 1, Neutrophil-activating protein 1, Permeability factor 1, PF1, Protein 3-10C, RP11-537A6.8, RPF1, small inducible cytokine subfamily B, member 8, SNX, SYNEXIN, T-cell chemotactic factor, tumor necrosis factor-induced gene 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3576
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
IL-8 (CXCL8)
Classification:
Recombinant Monoclonal
Concentration:
1.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P10145
Gene Symbols:
CXCL8
Immunogen:
A synthesized peptide derived from Human IL8
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry
Clone:
33A9
Conjugate:
Unconjugated
Gene:
CXCL8
Gene Alias:
(Ala-IL-8)77, (Ser-IL-8)72, Alveolar macrophage chemotactic factor I, alveolar macrophage-derived chemotactic factor-I, AMCF-I, ANX7, beta endothelial cell-derived neutrophil activating peptide, beta-thromboglobulin-like protein, chemokine (C-X-C motif) ligand 8, C-X-C motif chemokine 8, C-X-C motif chemokine ligand 8, CXCL8, cytokine 8, emoctakin, GCP/IL-8 protein I, GCP/IL-8 protein II, GCP/IL-8 protein III, GCP/IL-8 protein IV, GCP/IL-8 protein V, GCP/IL-8 protein VI, GCP1, GCP-1, Granulocyte chemotactic protein 1, IL8, IL-8, IL-8(1-77), IL-8(5-77), IL-8(6-77), IL-8(7-77), IL-8(8-77), IL-8(9-77), IL8/NAP1 form I, IL8/NAP1 form II, IL8/NAP1 form III, IL8/NAP1 form IV, IL8/NAP1 form V, IL8/NAP1 form VI, ILN, Interleukin, interleukin 8, Interleukin8, interleukin-8, interleuklin-8 precursor, LECT, LUCT, lung giant cell carcinoma-derived chemotactic protein, lymphocyte derived neutrophil activating peptide, Lymphocyte-derived neutrophil-activating factor, LYNAP, MDNCF, MDNCF-a, MDNCF-b, MDNCF-c, MONAP, Monocyte-derived neutrophil chemotactic factor, monocyte-derived neutrophil-activating peptide, NAF, NAP1, NAP-1, neutrophil activating peptide 1, neutrophil and T-lymphocyte chemotactic and activating factor, Neutrophil attractant/activation protein 1, neutrophil attractant/activation protein-1, Neutrophil-activating factor, neutrophil-activating peptide 1, Neutrophil-activating protein 1, Permeability factor 1, PF1, Protein 3-10C, RP11-537A6.8, RPF1, small inducible cytokine subfamily B, member 8, SNX, SYNEXIN, T-cell chemotactic factor, tumor necrosis factor-induced gene 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3576
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: GAA
Classification: Recombinant Monoclonal
Concentration: 0.8 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P10253
Gene Symbols: Gaa
Immunogen: A synthesized peptide derived from Human GAA
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: 5E5
Conjugate: Unconjugated
Gene: Gaa
Gene Alias: 70 kDa lysosomal alpha-glucosidase, 76 kDa lysosomal alpha-glucosidase, acid (Pompe disease, glycogen storage disease type II), acid alpha-glucosidase, acid maltase, Aglucosidase alfa, E430018M07Rik, Gaa, glucosidase alpha, acid, glucosidase, alpha, acid, glucosidase, alpha, acid (Pompe disease, glycogen storage disease type II), LYAG, Lysosomal alpha-glucosidase
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2548
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
GAA
Classification:
Recombinant Monoclonal
Concentration:
0.8 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P10253
Gene Symbols:
Gaa
Immunogen:
A synthesized peptide derived from Human GAA
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
5E5
Conjugate:
Unconjugated
Gene:
Gaa
Gene Alias:
70 kDa lysosomal alpha-glucosidase, 76 kDa lysosomal alpha-glucosidase, acid (Pompe disease, glycogen storage disease type II), acid alpha-glucosidase, acid maltase, Aglucosidase alfa, E430018M07Rik, Gaa, glucosidase alpha, acid, glucosidase, alpha, acid, glucosidase, alpha, acid (Pompe disease, glycogen storage disease type II), LYAG, Lysosomal alpha-glucosidase
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2548
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: L-Plastin
Classification: Recombinant Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P13796
Gene Symbols: LCP1
Immunogen: A synthesized peptide derived from Human LCP1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry
Clone: 29G10
Conjugate: Unconjugated
Gene: LCP1
Gene Alias: 65 kDa macrophage protein, AW536232, bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)), cb245, CP64, D14Ertd310e, DKFZp781A23186, epididymis secretory protein Li 37, fj24b12, FLJ25423, FLJ26114, FLJ39956, HEL-S-37, LC64P, LCP1, LCP-1, leucocyte-specific plastin 1, L-fimbrin, LPL, L-plastin, L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (PP65), L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P), lymphocyte cytosolic plastin 1, lymphocyte cytosolic protein 1, lymphocyte cytosolic protein 1 (L-plastin), Lymphocyte cytosolic protein-1 (plasmin), plastin 2, plastin 2, L, plastin-2, Pls2, pp65, wu:fj24b12
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3936
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
L-Plastin
Classification:
Recombinant Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P13796
Gene Symbols:
LCP1
Immunogen:
A synthesized peptide derived from Human LCP1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry
Clone:
29G10
Conjugate:
Unconjugated
Gene:
LCP1
Gene Alias:
65 kDa macrophage protein, AW536232, bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)), cb245, CP64, D14Ertd310e, DKFZp781A23186, epididymis secretory protein Li 37, fj24b12, FLJ25423, FLJ26114, FLJ39956, HEL-S-37, LC64P, LCP1, LCP-1, leucocyte-specific plastin 1, L-fimbrin, LPL, L-plastin, L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (PP65), L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P), lymphocyte cytosolic plastin 1, lymphocyte cytosolic protein 1, lymphocyte cytosolic protein 1 (L-plastin), Lymphocyte cytosolic protein-1 (plasmin), plastin 2, plastin 2, L, plastin-2, Pls2, pp65, wu:fj24b12
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3936
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG