FEMA550589

uPAR Monoclonal Antibody (A6E8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550589-Each-of-1 In Stock ₹ 40,127.64

FEMA550589 - Each of 1

₹ 40,127.64

In Stock

Quantity

1

Base Price: ₹ 40,127.64

GST (18%): ₹ 7,222.975

Total Price: ₹ 47,350.615

Antigen

uPAR

Classification

Monoclonal

Concentration

2 mg/mL

Formulation

PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q03405

Gene Symbols

PLAUR

Immunogen

Recombinant protein within human uPA Receptor aa 51-250/335.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Western Blot

Clone

A6E8

Conjugate

Unconjugated

Gene

PLAUR

Gene Alias

Cd87, MO3, Monocyte activation antigen Mo3, Par, plasminogen activator urokinase receptor 3, plasminogen activator, urokinase receptor, PLAUR, Plaur3, sCD87, soluble CD87, uPAR, U-PAR, uPAR-2, uPAR-3, u-plasminogen activator receptor form 2, urinary plasminogen activator receptor 2, urinary plasminogen activator receptor 3, URKR, urokinase plasminogen activator receptor, urokinase plasminogen activator surface receptor, urokinase-type plasminogen activator (uPA) receptor, urokinase-type plasminogen activator receptor

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

5329

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1

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Description

  • Positive control: U937 cell lysate, U937 cell lysate treated with 200 nM PMA for 72 hours
  • Predicted band size: 36 kDa Subcellular Location: Cell membrane, invadopodium membrane; Secreted
  • The urokinase-type plasminogen activator receptor is a key molecule in the regulation of cell-surface plasminogen activation and plays an important role in many normal as well as pathologic processes
  • The human PLAUR cDNA encodes 335 amino acids including a predicted signal peptide of 22 residues and a hydrophobic C-terminal portion
  • It produces a highly glycosylated protein of about 50 kD in monocytes where it is anchored to the plasma membrane by glycosyl-phosphatidylinositol linkage
  • PLAUR, also known as UPAR, is directly associated with the carbohydrate-binding domain of SELL in the membrane of neutrophils, an association analogous to that between PLAUR and beta-2 integrins
  • PLAUR-mediated calcium mobilization is SELL dependent
  • UPAR mRNA levels correlate with the invasive potential of endometrial carcinomas and show a 33-fold increase in UPAR mRNA levels in advanced clinical stage endometrial tumors compared with normal endometrial tissue
  • Furthermore, the increase in UPAR mRNA levels correlated linearly with the progression of disease stage
  • UPAR protein expressioin correlated positively with rate of recurrence and mortality in patients with endometrial cancer
  • UPAR appears to be a useful prognostic marker for advanced endometrial cancer.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA550589

--


Antigen:
uPAR

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q03405

Gene Symbols:
PLAUR

Immunogen:
Recombinant protein within human uPA Receptor aa 51-250/335.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Clone:
A6E8

Conjugate:
Unconjugated

Gene:
PLAUR

Gene Alias:
Cd87, MO3, Monocyte activation antigen Mo3, Par, plasminogen activator urokinase receptor 3, plasminogen activator, urokinase receptor, PLAUR, Plaur3, sCD87, soluble CD87, uPAR, U-PAR, uPAR-2, uPAR-3, u-plasminogen activator receptor form 2, urinary plasminogen activator receptor 2, urinary plasminogen activator receptor 3, URKR, urokinase plasminogen activator receptor, urokinase plasminogen activator surface receptor, urokinase-type plasminogen activator (uPA) receptor, urokinase-type plasminogen activator receptor

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5329

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

Thermo Scientific

FEMA550591

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Antigen:
SALL4

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9UJQ4

Gene Symbols:
SALL4

Immunogen:
Recombinant protein within human Sall4 aa 903-1053/1053.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
A7A5

Conjugate:
Unconjugated

Gene:
SALL4

Gene Alias:
5730441M18Rik, AA407717, AL022809, AW536104, C330011P20Rik, C78083, C78563, dJ1112F19.1, DRRS, HSAL4, SALL4, sal-like 4, sal-like 4 (Drosophila), sal-like protein 4, spalt like transcription factor 4, spalt-like transcription factor 4, Tex20, Zinc finger protein 797, zinc finger protein SALL4, ZNF797

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
57167

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

Thermo Scientific

FEMA550592

--


Antigen:
SALL4

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9UJQ4

Gene Symbols:
SALL4

Immunogen:
Recombinant protein within human Sall4 aa 903-1053/1053.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
A7A7

Conjugate:
Unconjugated

Gene:
SALL4

Gene Alias:
5730441M18Rik, AA407717, AL022809, AW536104, C330011P20Rik, C78083, C78563, dJ1112F19.1, DRRS, HSAL4, SALL4, sal-like 4, sal-like 4 (Drosophila), sal-like protein 4, spalt like transcription factor 4, spalt-like transcription factor 4, Tex20, Zinc finger protein 797, zinc finger protein SALL4, ZNF797

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
57167

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

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FEMA550595

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Antigen:
GSDMD

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P57764, Q9D8T2

Gene Symbols:
GSDMD

Immunogen:
Recombinant protein within human GSDMD aa 101-300/484.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Western Blot

Clone:
A8D7

Conjugate:
Unconjugated

Gene:
GSDMD

Gene Alias:
1810036L03Rik, AW558049, DF5L, Dfna5l, FKSG10, gasdermin D, gasdermin domain containing 1, gasdermin domain-containing protein 1, Gasdermin-D, Gasdermin-D, C-terminal, Gasdermin-D, N-terminal, GSDMD, GSDMDC1, GSDMD-CT, GSDMD-NT, M2-4

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
69146, 79792

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b